The New York Yankees will visit the Baltimore Orioles on Sunday afternoon at Camden Yards. Sunday’s matchup is shaping up as a key late-season confrontation. The Yankees are pushing hard for playoff positioning while the Orioles are out of the race and trying to play spoiler. Here, I break down this AL East matchup and give you my Yankees vs Orioles prediction today.
Our Yankees vs Orioles Pick
- Pick: Yankees −1.5
- Confidence: ★★★★☆
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Game Snapshot
- Matchup: New York Yankees vs Baltimore Orioles
- Date & Time: Sunday, September 21, 2025,1:35 PM ET
- Starting Pitchers:
- Yankees: Cam Schlittler (3-3, 3.41 ERA)
- Orioles: Kyle Bradish (1-1, 2.45 ERA)
- Stadium: Oriole Park at Camden Yards, Baltimore, MD
- Broadcast: MASN & YES
Key Storylines
Pitching matchup
Cam Schlittler is still relatively unproven long-term but has shown good stuff this season. He has a 3.41 ERA and averages over a strikeout per inning. Kyle Bradish has posted a strong 2.45 ERA in limited innings. He’s kept hitters off balance and hasn’t given up many hits since returning from a prolonged injury absence. Yet Bradish also has a smaller sample size under his belt and regression could always be around the corner.
Recent Team Streaks
- The Yankees have won four of their last five games and will try to finish this series strong.
- The Orioles have lost two of their last three games going into the finale of this four-game set.
Best Player Props
| Player | Prop |
|---|---|
| Aaron Judge | Over 1.5 total bases |
| Giancarlo Stanton | Anytime home run |
| Kyle Bradish | Over 5.5 strikeouts |
Betting Trends & H2H
- The Yankees lead the season series 5-4 over the Orioles in 2025.
- The Yankees have won four of their last five matchups against the Orioles this year.
- New York is 43-37 on the road in 2025.
- Baltimore is 37-40 at home on the season.
Yankees vs Orioles Model Projection
| Score Projection: | New York Yankees 5 – Baltimore Orioles 2 |
| Win Probability: | Yankees 65%, Orioles 35% |
Final Thoughts
This is a game where everything leans in favor of the Yankees. They have the momentum, a deeper offense, and a pitching matchup that they can compete in. The Orioles have shown flashes, but don’t have enough consistency to hang with a New York team with playoff aspirations. I’m going to lay the runline with the Yankees as favorites in this contest, as their firepower should get them another important win for their playoff chances.
