The New York Mets and Chicago Cubs will face off at Wrigley Field on Tuesday night. Tuesday’s matchup between these teams is huge for both sides. The Mets (80-76) are tied for the final National League Wild Card spot. The Cubs (88-68) have already clinched postseason play and are trying to secure the best position they can before the Wild Card round. Before these teams face off in Chicago, continue reading to get my Mets vs Cubs prediction for Tuesday night.
Our Mets vs Cubs Pick
- Pick: Chicago Cubs Moneyline
- Confidence: ★★★☆☆
Game Snapshot
- Matchup: New York Mets vs Chicago Cubs
- Date & Time: Tuesday, September 23, 2025, 7:40 p.m. ET
- Starting Pitchers: Cade Horton (Cubs) vs David Peterson (Mets)
- Stadium: Wrigley Field, Chicago, IL
- Broadcast: TBS
Key Storylines
- Pitching matchup: Chicago’s Cade Horton has had an excellent season. His ERA is well under league average and he’s earned clutch wins, especially at home. David Peterson of the Mets has been solid but not dominant. The Cubs have a slight edge in the starting pitching department going into this matchup. Chicago’s bullpen also tends to be more reliable down the stretch.
- Key Players: On the Mets side, Juan Soto has 42 home runs and remains a dangerous bat for New York. Pete Alonso and Francisco Lindor each bring power for the Mets as well. For the Cubs, hitters like Nico Hoerner and Seiya Suzuki will be vital to their chances of winning this key matchup.
- Recent team streaks: Chicago has dropped four straight games to the Cincinnati Reds, which raises questions about their offense and confidence. The Mets are also in a slump, having lost two straight.
Best Player Props
| Player | Prop Type | Pick |
|---|---|---|
| Cade Horton | Strikeouts | Over 4.5 strikeouts |
| Pete Alonso | Total Bases | Over 1.5 total bases |
| Nico Hoerner | Hits + Runs + RBIs | Over 1.5 combined |
Betting Trends & H2H
- The Mets hold a 2-1 lead in their season series against the Cubs in 2025.
- New York is 31-44 in their road games so far this season.
- Chicago is 46-29 in their home games in 2025.
Mets vs Cubs Model Projection
- Score Projection: Cubs 4 – Mets 2
- Win Probability: Cubs 55%, Mets 45%
Final Thoughts
The Cubs enter this game with a slight edge. They have a strong home record, a sharper starter in Cade Horton, and plenty to play for in terms of securing a favorable position for the postseason. The Mets bring plenty of star power, but their pitching and recent road performances are an issue. I’ll take the Cubs to win this game on the moneyline and to threaten the Mets’ position as one of the three Wild Card teams in the National League with just a few more days remaining in the regular season.
