Minnesota Twins vs Los Angeles Angels Prediction – 9/10/2025
The Minnesota Twins and Los Angeles Angels will meet for the third day in a row on Wednesday. This series finale in Anaheim closes out a series where both teams have taken a game so far. Minnesota has sputtered of late on the road, while the Angels have not been reliable at home themselves. Both teams are well out of Wild Card contention but will look for a series clinching win in this game nonetheless. Before first pitch from Anaheim, keep reading to get my Twins vs Angels prediction.
Our Twins vs Angels Pick
- Pick: Over 8.5 runs
- Confidence: ★★★☆☆
- Wednesday MLB Bonus Bets: Use our DraftKings Sportsbook bonus to turn a $5 into $200 in bonus bets INSTANTLY. Just hit the Claim Bonus button to get started!
Bet $5, Get $200 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $200 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Matchup: Minnesota Twins vs Los Angeles Angels
- Date & Time: Wednesday, September 10, 2025, 4:07 p.m. ET
- Starting Pitchers: Taj Bradley vs José Soriano
- Stadium: Angel Stadium of Anaheim, Anaheim, CA
- Broadcast: FanDuel Sports West in Southern California, Fanduel Sports North in Minnesota
Key Storylines
- Both of these teams are not mathematically eliminated from Wild Card contention just yet. But that time is fast approaching as both teams are nine games out or more in the AL Wild Card standings.
- Both teams have enjoyed an offensive explosion at one point or another in this series. The Twins put up 12 runs in the first game and the Angels responded with 12 runs in the second. The team that does the best job of preventing another offensive outburst from their opponent should win this game.
Pitching matchup
- Taj Bradley, Twins: It will be Taj Bradley on the mound for Minnesota to start this game. Bradley is 6-7 with a 4.92 ERA for the season. He will look to neutralize the bats of the Angels and eat up innings after the Twins bullpen had to do a ton of work in yesterday’s 12-2 loss to the Angels.
- José Soriano, Angels: Soriano comes into this start at 10-10 with a 4.07 ERA and 1.37 WHIP across 163.2 innings. His heavy sinker/curve mix creates weak contact and grounders when he’s in the zone. The Twins’ lineup has run high strikeout rates and a middling road OPS vs righties, which gives Soriano a path to bounce back if he limits walks early.
Recent team streaks
- Minnesota had a two-game winning streak snapped in their loss to the Angels yesterday.
- The Angels have won two of their last three games.
Best Player Props
| Player | Prop | Pick |
|---|---|---|
| Taj Bradley | Strikeouts | Over 5.5 |
| José Soriano | Strikeouts | Under 5.5 |
| Byron Buxton | Total Bases | Over 1.5 |
| Taylor Ward | Total Bases | Over 1.5 |
| Jo Adell | Home Run | Over 0.5 |
Betting Trends & H2H
- Minnesota holds a 4-1 lead in their season series with the Angels.
- The over is 3-2 in games between these teams so far this season.
Twins vs Angels Model Projection
- Score Projection: Twins 4 – Angels 6
- Win Probability: Angels 56%, Twins 44%
Final Thoughts
I think we are going to see some offensive fireworks no matter who ends up winning this game. Both teams are gifted offensively despite lacking consistency. While I don’t expect another double-digit scoring game from one of these teams, I do think that they will combine to go over the total on Wednesday afternoon.
