Minnesota Twins vs Detroit Tigers Pick – 8/4/2025

The Minnesota Twins will travel to Comerica Park to face the Detroit Tigers on Monday night. The Tigers are leading the AL Central and they will look to extend their lead against a Twins team that has struggled so far this season. Here, I break down this matchup and give you my Twins vs Tigers prediction for Monday night.


Our Twins vs Tigers Pick

  • Pick: Tigers -1.5
  • Confidence: ★★★★☆
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Game Snapshot

MatchupMinnesota Twins vs. Detroit Tigers
Date & TimeAugust 4, 2025, 6:40 p.m. ET
Starting PitchersCasey Mize (DET) vs. Undecided (MIN)
StadiumComerica Park, Detroit, MI
BroadcastFDSDET, MNNT

Key Storylines to Watch

  • Pitching Form: Casey Mize is on the mound for the Tigers in this game. He is 9-4 and has a 3.43 ERA for the season. Mize has done a nice job as a complementary piece behind the great Tarik Skubal in the Detroit rotation this year. Minnesota has yet to decide on a starting pitcher and who they go with will have a big impact on their chances.

  • Bullpen Usage: Both teams are in the bottom half of the league in terms of bullpen ERA. Minnesota’s bullpen could be even worse than their numbers show going forward after trading Jhoan Duran at the trade deadline.

  • Team Momentum: Both teams dropped two out of three games in their most recent series. The Twins lost two out of three games to the Cleveland Guardians over the weekend. Detroit lost two out of three on the road to the Philadelphia Phillies.


Best Player Props

PlayerPropPick
Riley GreeneHome RunsOver 0.5
Gleyber TorresTotal BasesOver 1.5
Casey MizeStrikeoutsOver 5.5

  • Detroit leads the season series with Minnesota 4-2 heading into Monday’s game.

  • The Tigers have won two straight against the Twins heading into this contest.

  • The under is 4-2 in the games between these teams in 2025.

  • Detroit is 36-21 at home this season. Minnesota is 22-35 on the road.


Twins vs Tigers Model Projection

Projected Score: Tigers 6 – Twins 4
Win Probability: Tigers 56% | Twins 44%


Final Thoughts

Casey Mize has been a real difference maker for the Detroit Tigers so far this season. I expect Mize to continue to pitch well in this game and for the Tigers to win and cover the runline at home against a Twins team that has lost four of its last five games.


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Home MLB Picks Minnesota Twins vs Detroit Tigers Pick – 8/4/2025