Milwaukee Brewers vs Seattle Mariners Prediction – 7/23/2025

The Milwaukee Brewers visit Seattle to wrap up a three‑game series at T‑Mobile Park on Wednesday. Seattle enters as a modest favorite across sportsbooks after snapping Milwaukee’s long winning streak last night. Here, I break down whether the Mariners will get a second straight win over Milwaukee, or if Milwaukee will get back into the win column with my Brewers vs Mariners prediction for the day.

Our Brewers vs Mariners Pick

  • Pick: Mariners moneyline
  • Confidence: ★★★★
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Game Snapshot

  • Matchup: Milwaukee Brewers @ Seattle Mariners
  • Date & Time: Wednesday, July 23, 2025, 3:40 p.m. ET
  • Starting Pitchers: Quinn Priester (8–2, 3.33 ERA) vs. Luis Castillo (7–5, 3.21 ERA)
  • Stadium: T‑Mobile Park, Seattle, WA
  • Broadcast: ROOT Sports NW and FDSWI

Key Storylines

  • Seattle is looking to gain ground in AL West and hold their Wild Card positioning with a win here.
  • Milwaukee saw an 11‑game winning streak come to an end last night. That streak included sweeps over both Los Angeles teams and a stretch of dominant pitching that has produced the best ERA in the National League since mid‑May.

Pitching Form

  • Quinn Priester: Priester is 8–2 with a 3.33 ERA. He is coming off a shutout start on July 18. Seattle has yet to face him this season.
  • Luis Castillo: The Mariners vet is 7–5 with a 3.21 ERA. His last three outings included two quality starts. He’s known for keeping hitters off‑balance. But Milwaukee’s offense can jump on mistakes.

Bullpen Usage

Both of the bullpens in this game have been solid this year. They have each helped their teams to secure a win in this series as well. The pens could help to decide this rubber match, especially if the starting pitching matchup is as competitive as we expect it to be.

Best Player Props

PlayerProp
Jackson Chourio (MIL)Over 0.5 HR
Luis Castillo (SEA)Over 5.5 strikeouts
Christian Yelich (MIL)Over 1.5 Total Bases
  • These teams have split their season series 1-1 so far in 2025.
  • The Brewers are 27-18 in day games this season. Seattle is 24-14 in day games on the year.

Brewers vs Mariners Model Projection

Score Projection: Brewers 4 – Mariners 5

Win Probability: Brewers 44%, Mariners 56%

Final Thoughts

I project this being a close game in the Pacific Northwest on Wednesday. But someone has to win it and I think that team will be the Mariners. Seattle got a gritty victory over the Brew Crew on Tuesday thanks to some great pitching. I expect a strong outing from Castillo in this game as well and for Seattle to take two out of three in this series.


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Home MLB Picks Milwaukee Brewers vs Seattle Mariners Prediction – 7/23/2025