Miami Marlins vs St. Louis Cardinals Prediction – 7/29/2025

The Miami Marlins are set to face the St. Louis Cardinals on Tuesday night at Busch Stadium. The Cardinals won the opening game of this series in dominant fashion and will look for a second straight win over Miami tonight. Keep reading to get my analysis of this matchup, including my Marlins vs Cardinals prediction.


Our Marlins vs Cardinals Prediction

  • Pick: St. Louis Cardinals -1.5
  • Confidence: ★★★★☆
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Game Snapshot

MatchupMiami Marlins vs. St. Louis Cardinals
Date & TimeJuly 29, 2025, 7:45 PM ET
Starting PitchersSandy Alcantara vs. Sonny Gray
StadiumBusch Stadium
BroadcastMLB.tv

Key Storylines to Watch

  • Pitching Form: The starting pitchers for this contest are Sandy Alcantara and Sonny Gray. Alcantara has struggled mightily for the Marlins this season. He is 5-9 with a 6.66 ERA for the year. He will need to raise his level on the bump to compete with Gray. Gray is 10-4 and has a respectable 4.33 ERA for the season.

  • Bullpen Usage: The Cardinals’ bullpen has been reliable. They helped hold the Marlins to one run in the first game of this series. St. Louis ranks sixth in the league in bullpen ERA for the year.
  • Team Momentum: The Cardinals snapped a two-game losing streak with their win over the Marlins on Monday night. The Marlins have dropped two games in a row coming into this matchup in St. Louis.


Best Player Props

Kyle Stowers (MIA)Home RunsOver 0.5
Nolan Arenado (STL)Total BasesOver 1.5

  • The Cardinals are 1-0 against the Marlins so far this year.

  • The first game between these teams went under the total of 8.5 runs. There were eight total runs scored.

  • St. Louis is 32-22 at home this season after winning at home on Monday.

  • Miami dropped to 26-26 on the road for the year with their loss on Monday night.

Marlins vs Cardinals Model Projection

Projected Score: Cardinals 5 – Marlins 3
Win Probability: Cardinals 60% | Marlins 40%


Final Thoughts

Any chance I get to fade Sandy Alcantara on the mound is a chance I am willing to take right now. The Cardinals have the starting pitching edge with Gray on the mound against Alcantara. They also have the edge in the bullpen department in this matchup. I am taking the Cardinals to win and cover the runline at home tonight.


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Home MLB Picks Miami Marlins vs St. Louis Cardinals Prediction – 7/29/2025