Los Angeles Dodgers vs Pittsburgh Pirates Pick – 9/3/2025

The Los Angeles Dodgers and Pittsburgh Pirates will play the second game of a three-game series on Wednesday night. The Pirates shocked the Dodgers at PNC Park on Tuesday and will look to deliver another upset in this game. Before Pittsburgh and Los Angeles take the field on Wednesday, continue reading to get my Dodgers vs Pirates prediction from Pittsburgh.

Our Dodgers vs Pirates Pick

  • Pick: Pirates Moneyline
  • Confidence: ★★★☆☆
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Game Snapshot

  • Matchup: Los Angeles Dodgers vs Pittsburgh Pirates
  • Date & Time: Wednesday, September 3, 2025, 6:40 p.m. ET
  • Starting Pitchers: Shohei Ohtani (LAD) vs Braxton Ashcraft (PIT)
  • Stadium: PNC Park, Pittsburgh, PA
  • Broadcast: SportsNet PT and SportsNet LA

Key Storylines

Pitching matchup

Shohei Ohtani takes the hill for LA in this game. He is 1-1 with a 4.18 ERA and a WHIP of 1.21. He’s struggled away from Dodger Stadium with a road ERA north of 6.00 this season. That will make run support from the Dodgers’ lineup all the more important. Pittsburgh will rely on Braxton Ashcraft to start this game on the mound. He brings a stingy 2.58 ERA into this game and has fared well since the All-Star break. He offers the Pirates a chance to silence the visitors early on.

Key Players

  • Shohei Ohtani: Ohtani leads the Dodgers with 46 home runs and 87 RBI. He will be important both on the mound and at the plate.
  • Andy Pages: Pages has hit in eight straight games and will look to extend that streak here.
  • Oneil Cruz and Bryan Reynolds: Pittsburgh’s top offensive threats will look to build on the team’s nine-run performance on Tuesday.

Recent team streaks

  • Dodgers: LA has dropped three of their last four games after losing to the Pirates on Tuesday.
  • Pirates: Pittsburgh won Game 1 of this series behind some timely hitting. They are riding a 7-3 stretch over their last 10 games.

Best Player Props

PlayerProp
Shohei OhtaniUnder 5.5 Strikeouts
Mookie BettsUnder 1.5 Total Bases
Andy PagesUnder 1.5 Total Bases
  • The season series between the Pirates and Dodgers is tied 2-2 going into this matchup.
  • All four games between these teams have been decided by two runs or more this year.
  • The over has hit in three of the four games between these teams on the year.

Dodgers vs Pirates Model Projection

Score Projection: Dodgers 4 – Pirates 5

Win Probability: Dodgers 51%, Pirates 49%

Final Thoughts

I think the Pirates have a chance to pull off another upset of the Dodgers tonight. Ohtani is on the mound and that will attract a ton of bets on the Dodgers. But Ohtani hasn’t been great on the road so far this season when pitching and that could continue here. I’ll take a flyer on the Pirates here in hopes that they can step up for the second night in a row.


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Home MLB Picks Los Angeles Dodgers vs Pittsburgh Pirates Pick – 9/3/2025