Houston Astros vs Seattle Mariners Prediction – 7/20/2025

The Houston Astros and Seattle Mariners close out their three-game series at T-Mobile Park on Sunday. This game has significant implications in the AL West. The Astros’ lead in the AL West is down to three games after the Mariners took the first two games of this weekend series. A sweep for the Mariners would tighten things up even further. Here, I break down this game and give you my Astros vs Mariners prediction to help you determine whether or not that sweep will play out.

Our Astros vs Mariners Pick

• Pick: Seattle Mariners to win
• Confidence: ★★★★☆
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Game Snapshot

• Matchup: Houston Astros vs Seattle Mariners
• Date & Time: July 20, 2025, 4:10 PM ET
• Starting Pitchers: Hunter Brown vs Bryan Woo
• Stadium: T-Mobile Park, Seattle, WA
• Broadcast: ROOT Sports NW, SCHN

Key Storylines

• Pitching form: Hunter Brown gets the start for Houston today. He is 9-4 with a 2.43 ERA in 2025. He will be opposed by Bryan Woo of the Mariners. Woo is 8-4 and has a 2.75 ERA. Both of these pitchers are delivering at an All-Star level this year and a matchup between them should be electric stuff.
• Bullpen usage: Both bullpens had to work hard last night in a game that went 11 innings. The bullpen that can recover from that the best will give their team a great chance to win this game.
• Recent team streaks: The Astros have lost three games in a row coming into today’s action. Seattle has won five games in a row and have pulled to within three games of the Astros in the AL West standings.

Best Player Props

Betting Trends & H2H

• Seattle now leads the season series between these teams 5-4 after last night’s 11-inning win.
• The over/under is 1-1 between these teams in the first two games of this three-game set.
• Seattle has scored 13 runs combined over their last two games against the Astros.

Astros vs Mariners Model Projection

Score Projection: Seattle 5 – Houston 4

Win Probability: Seattle 50.2%, Houston 49.8%

Final Thoughts

Both starting pitchers have the potential to take this game over for their respective teams. But I am going to back Bryan Woo to do that at home for the Mariners. Seattle is playing better baseball than Houston right now, and that should continue with the Mariners grabbing a series sweep and inching closer to Houston in the standings.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.