Houston Astros vs Detroit Tigers Prediction – 8/19/2025

The Detroit Tigers blew the Houston Astros out in the first game of their series on Monday night. Runs could be hard to come by for the Astros again on Tuesday as they face Tigers ace Tarik Skubal. Detroit is favored in a game that features a terrific pitching matchup. Before both lineups try to solve the pitchers on each side, you can continue reading to get my breakdown of this game and my Astros vs Tigers prediction.

Our Astros vs Tigers Pick

  • Pick: Detroit Tigers to win
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Houston Astros vs Detroit Tigers
  • Date & Time: Tuesday, August 19, 2025, 6:40 p.m. ET
  • Starting Pitchers: Hunter Brown (Astros) vs Tarik Skubal (Tigers)
  • Stadium: Comerica Park, Detroit, MI
  • Broadcast: TBS

Key Storylines

Pitching matchup

Hunter Brown has delivered another strong season for Houston. He has an elite 29.4% strikeout rate this season. He has a 2.45 ERA and 2.92 FIP entering this game. He limits hard contact well. His 5.5% barrel rate is proof that Brown has been hard for opposing hitters to time up on a consistent basis.

Opposing Brown is the reigning AL Cy Young winner Tarik Skubal. Skubal is third in the league in ERA and strikeouts so far this season. He is 11-3 with a 2.42 ERA and has not taken a loss in over a month. Skubal will look to prolong the struggles of the Astros’ offense after Houston was shut out on Monday.

Key Players

  • Detroit: Riley Greene leads the Tigers in home runs this season and he hit a home run for Detroit on Monday. Greene will look to lead the Tigers’ offense to some scoring against Hunter Brown in this game.
  • Houston: The entire Houston offense is the key to this game for them. Their goal has to be to drive up the pitch count of Skubal in order to get him out of the game and give them a chance to win.

Recent Team Streaks

  • Houston has lost two games in a row and three of their last four.
  • Detroit has won four of its last five games and is a favorite to win this contest as well.

Key Stat Leaders

CategoryAstrosTigers
Home RunsJosé Altuve – 22 HRRiley Greene – 29 HR
Starting Pitcher StrikeoutsHunter Brown – 164 KTarik Skubal – 190 K
RBIChristian Walker – 65 RBIRiley Greene – 92 RBI
  • The season series between these teams is tied 2-2 going into Tuesday’s game.
  • Detroit has won two straight games over Houston after the Astros won the first two games of the season series.
  • All four games between these teams this season have had 10+ total runs scored.

Astros vs Tigers Model Projection

Score Projection: Tigers 4 – Astros 3

Win Probability: Tigers 54%, Astros 46%

Final Thoughts

We are not likely to see another game with 10+ total runs scored between these teams on Tuesday night. Both Brown and Skubal are going to make life difficult on the lineups in this matchup. But I think that Skubal is going to do just a bit better than Brown and put the Tigers in a position to win this game. I’ll take the Tigers on the moneyline in what should be a great game from Detroit.


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Home MLB Picks Houston Astros vs Detroit Tigers Prediction – 8/19/2025