Houston Astros vs Baltimore Orioles Prediction – 8/23/2025

The Houston Astros and Baltimore Orioles will face off for the third straight day on Saturday night. The Astros have won the first two games of this series on the road and will look to get a third straight with a win here. Before this matchup begins from Baltimore, you can find my analysis for the game below along with my Astros vs Orioles prediction.

Our Astros vs Orioles Pick

  • Pick: Astros moneyline
  • Confidence: ★★★☆☆
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Game Snapshot

  • Matchup: Houston Astros vs Baltimore Orioles
  • Date & Time: Saturday, August 23, 2025, 7:05 p.m. ET
  • Starting Pitchers:
    • Astros – Cristian Javier (1-1, 3.38 ERA)
    • Orioles – Dean Kremer (9-9, 3.97 ERA)
  • Stadium: Oriole Park at Camden Yards, Baltimore, MD
  • Broadcast: MASN and SCHN

Key Storylines

Pitching matchup

Dean Kremer comes in with solid recent form. He’s posted a 2.14 ERA over three starts in August and dominated Houston recently with a seven-inning gem in which he struck out seven. His lifetime numbers against the Astros are strikingly good. He has a 1.47 ERA and .188 batting average allowed in five career starts versus Houston.

Cristian Javier returns from injury with a 3.38 ERA over a limited number of innings this season. His last outing versus Baltimore ended early due to illness but he was pitching well before his departure.

Key Players

  • Orioles: Gunnar Henderson had two hits for the Orioles on Friday and will need to continue to produce to help his team get on the board in this series.
  • Jeremy Pena and Christian Walker both belted three-run home runs in Houston’s win over Baltimore on Friday night and they will look to make an impact in this contest.

Recent Team Streaks

  • The Astros have won two straight games after getting swept by the Detroit Tigers in their last series.
  • Baltimore has dropped the first two games of this series after entering the series on a three-game winning streak.

Best Player Props

PlayerProp
Gunnar HendersonOver 1.5 Total Bases
Christian WalkerOver 1.5 Total Bases
Jeremy PenaOver 1.5 Total Bases
  • Houston holds a 3-2 lead in the season series against the Orioles.
  • Four of the five games between these teams have been decided by two runs or more.
  • Four straight games between these teams have gone over their respective totals.

Astros vs Orioles Model Projection

Score Projection: Orioles 5 – Astros 6

Win Probability: Astros 52%, Orioles 48%

Final Thoughts

The Astros have dominated the recent proceedings between these teams. I expect that to continue in this contest. While we haven’t seen a lot of Cristian Javier this season, I think that he has more upside than Dean Kremer in the starting pitching matchup. That should open the door for another strong offensive showing for Houston. I’ll take the Astros to win this one on the moneyline on the road.


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Home MLB Picks Houston Astros vs Baltimore Orioles Prediction – 8/23/2025