Detroit Tigers vs Pittsburgh Pirates Prediction – 7/22/2025
The Detroit Tigers were beaten by Paul Skenes and the Pittsburgh Pirates in the opening game of their three-game series on Monday night. The Tigers will look to bounce back from that loss on Tuesday without Skenes on the bump. Here, I have broken this interleague game down from all angles. You can continue reading to get my Tigers vs Pirates prediction for Tuesday night. Score Projection: Detroit Tigers 5 – Pittsburgh Pirates 3 Win Probability: Tigers 57%, Pirates 43% This is a prime spot for the Tigers to bounce back after their loss to Skenes and the Pirates on Monday night. Skenes is no longer someone the Tigers have to contend with during this series. Now the Tigers will have the starting pitching advantage with Mize on the bump. Look for Mize to help the Tigers to get a win here that will move Detroit back to 20 games above .500 for the year.Our Tigers vs Pirates Pick
Game Snapshot
Key Storylines
Best Player Props
Player Prop Line Riley Greene Home runs Over 0.5 Casey Mize Strikeouts Over 5.5 Gleyber Torres Total bases Over 1.5 Betting Trends & H2H
Tigers vs Pirates Model Projection
Final Thoughts
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ATS.io features affiliate links to licensed online casinos, sportsbooks, and gambling platforms. That means if you click on them and end up signing up or making a deposit, we might earn a commission at no extra cost to you. We only work with licensed and reputable online casinos, social casinos and sportsbooks. Our content whether it’s reviews, guides, or betting tips is written with the goal of being honest, helpful, and based on real experience. While we do earn through affiliate partnerships, it doesn’t affect our recommendations. If a site isn’t safe or doesn’t meet our standards, we won’t promote it. Simple as that. We also take responsible gambling seriously. We encourage all our readers to gamble safely, set limits, and know when to take a break. Have questions? Feel free to reach out. We’re always happy to chat.
