Detroit Tigers vs Minnesota Twins Pick – 8/16/2025

The Detroit Tigers and Minnesota Twins will meet at Target Field on Saturday for the third game of a four-game series. The Tigers have had the upper hand in this series so far and have taken the first two games. They will look to lock up the series win in just three games with a win tonight. Before first pitch from Minneapolis, continue reading to get my Tigers vs Twins prediction for Saturday’s game.

Our Tigers vs Twins Pick

  • Pick: Tigers moneyline
  • Confidence: 4/5
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Game Snapshot

  • Matchup: Detroit Tigers vs Minnesota Twins
  • Date & Time: Saturday, August 16, 2025, 7:15 PM ET
  • Starting Pitchers: Casey Mize (Detroit) vs Zebby Matthews (Minnesota)
  • Stadium: Target Field, Minneapolis, MN
  • Broadcast: FOX

Key Storylines

Pitching matchup

Casey Mize will make the start for the Tigers in this game. He is holding an 11–4 record and 3.50 ERA on the season. His recent outings have included quality starts and success on the road. He has a 4–3 record with a 3.52 ERA in 53.2 road innings. Zebby Matthews gets the start for the Twins. He enters with a 3–4 record and 5.11 ERA. His ERA is higher at home than it has been on the road and the Tigers will have an opportunity to take advantage of that.

Key Players

  • Dillon Dingler was a key player for the Tigers on Friday. He knocked in three runs and he could give the Tigers a huge lift offensively again tonight.
  • Javier Baez had two RBI for Detroit on Friday and he will try and provide a spark from the bottom of the order.

Recent Team Streaks

  • Detroit has won three games in a row and four of its last five.
  • Minnesota has lost the first two games of this series and they have lost four of their last five games in total.

Best Player Props

PlayerProp
Riley GreeneOver 1.5 Total Bases
Casey MizeOver 5.5 Strikeouts
Javier BaezOver 0.5 RBI
  • The Tigers hold a 7-4 lead in their season series against the Twins.
  • The first two games of this series have gone under their respective totals at Target Field.
  • The road team has won the last four games played between these AL Central rivals.

Tigers vs Twins Model Projection

Score Projection: Tigers 5 – Twins 3

Win Probability: Tigers 53%, Twins 47%

Final Thoughts

The Tigers have proven that being on the road against the Twins isn’t a daunting task for them. They have controlled the first two games of this series for the most part and I expect them to control this game as well. Casey Mize gives the Tigers a major starting pitching edge that they will utilize to grab this game and hand the Twins their third loss in a row.


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Home MLB Picks Detroit Tigers vs Minnesota Twins Pick – 8/16/2025