Detroit Tigers vs Miami Marlins Pick – 9/12/2025

The Detroit Tigers and Miami Marlins will meet on Friday night at loanDepot park. This series opener features two clubs heading in different directions this season. It also features an incredible pitching matchup featuring two pitchers who have won Cy Young awards before in their careers. Before this game begins in South Florida, continue reading to get my Tigers vs Marlins prediction for tonight.

Our Tigers vs Marlins Pick

  • Pick: Detroit Tigers -1.5
  • Confidence: 4/5
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Game Snapshot

  • Teams: Detroit Tigers vs Miami Marlins
  • Date and Time: Friday, September 12, 2025, 7:10 PM ET
  • Starting Pitchers: Tarik Skubal vs Sandy Alcantara
  • Stadium: loanDepot park, Miami, FL
  • Broadcast: FanDuel Sports Network Florida, FanDuel Sports Network Detroit

Key Storylines

  • The pitching matchup in this game is the biggest storyline by a wide margin. Tarik Skubal and Sandy Alcantara are going to start this game on the bump for their respective teams. That is going to be a ton of fun to watch, even if Alcantara has struggled somewhat over the last couple of seasons.
  • The Tigers have more or less locked up the AL Central title this season. They are 8.5 games up on the next team in the division and they will try to move one step closer to getting the division sewn up with a win here.
  • Miami is all but out of hope in the NL Wild Card race. They are eight games back and running out of time to make up the difference.

Pitching outlook

Tarik Skubal has been phenomenal for the Tigers this season. He is 13-4 with a 2.10 ERA and will try to keep performing at an all-world level here against the struggling Marlins. The Marlins are going with Sandy Alcantara on the bump for this game. Alcantara is a former Cy Young winner but has had a rough go of things this season. He is 8-12 with a 5.67 ERA.

Recent team streaks

  • Detroit took two out of three games against the New York Yankees in their last series.
  • Miami has won two straight games over the Washington Nationals in their most recent series.

Best Player Props

PlayerMarketRecommendation
Riley Greene, DETTotal BasesOver 1.5
Riley Greene, DETHome RunYes
Tarik SkubalStrikeoutsOver 7.5
Xavier Edwards, MIATotal BasesUnder 1.5
  • This is the first meeting between these teams this season.
  • Detroit is 38-34 on the road this season.
  • Miami is 34-41 at home in 2025.

Tigers vs Marlins Model Projection

Score Projection: Detroit 5, Miami 3

Win Probability: Detroit 62%, Miami 38%

Final Thoughts

Tarik Skubal is on the mound for the Tigers in this game and that has typically meant great things for Detroit. Alcantara is always capable of pitching like he did in his Cy Young season in any given game. But I don’t think he will be able to match what Skubal does throughout this contest. I will take the Tigers to win and cover the runline on the road.


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Home MLB Picks Detroit Tigers vs Miami Marlins Pick – 9/12/2025