Cleveland Guardians vs Houston Astros Prediction – 7/8/2025

The Cleveland Guardians snapped their long losing streak by beating the Houston Astros on Monday night. Those two teams will do battle again on Tuesday at Daikin Park in Houston. The Astros are favored as they look to even this three-game series at a game apiece. Continue reading to get my analysis ahead of this game, including my Guardians vs Astros prediction.

Our Guardians vs Astros Pick

  • Pick: Astros -1.5
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: Cleveland Guardians at Houston Astros
  • Date & Time: Tuesday, July 8, 2025, 8:10 p.m. ET
  • Starting Pitchers: Joey Cantillo (CLE) vs Hunter Brown (HOU)
  • Stadium: Daikin Park, Houston, TX
  • Broadcast: SCHN and CLEG

Key Storylines

Pitching form

Hunter Brown has emerged as one of baseball’s elite arms. He has a 9-3 record and a 1.82 ERA going into this start. He’s also extremely tough to beat at home. Joey Cantillo is 1-0 with a modest 3.41 ERA and 11.65 K/9. Cantillo will have to pitch one of his best-ever games if he wants to get the better of Brown and the Astros tonight.

Bullpen usage

Houston’s bullpen has been nothing short of spectacular. They rank second in the league in bullpen ERA at 3.24. Only the San Francisco Giants have had more success going to their relief pitchers than the Astros in 2025.

Recent team streaks

Houston is coming off of a sweep of the Los Angeles Dodgers. But they dropped the first game of this series to the Guardians. Cleveland snapped a 10-game losing streak with their win on Monday in Houston.

Best Player Props

PlayerPropLine
Jose Ramirez (CLE)Over 0.5 Home Runs+390
Hunter Brown (HOU)Over 6.5 Strikeouts-145
Isaac Paredes (HOU)Over 1.5 Total Bases+130
  • The season series between these teams is tied at two games apiece.
  • Cleveland is 21-25 on the road this season. Houston is 32-15 at home despite Monday’s setback.
  • Both teams have gone under the total in 56% of their games this year.

Guardians vs Astros Model Projection

Score Projection: Cleveland 3 – Houston 6

Win Probability: Cleveland 28%, Houston 72%

Final Thoughts

The Guardians have to feel good that they were able to end their 10-game losing streak last time out. But I expect their joy to be short-lived. Hunter Brown is having a great season for the Astros this year, and I expect him to come out firing in this game as well. Look for the Astros to win this game and cover the runline at home to bounce back from their surprising defeat on Monday.


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Home MLB Picks Cleveland Guardians vs Houston Astros Prediction – 7/8/2025