Cleveland Guardians vs Chicago White Sox Prediction – 8/8/2025
The Cleveland Guardians have dominated the Chicago White Sox in their meetings so far this season. They will look to continue to have the upper hand against the White Sox on Friday night. These AL Central rivals will begin a three-game series at Rate Field in this matchup. I have broken the game down and you can find my Guardians vs White Sox prediction below.
Our Guardians vs White Sox Pick
- Pick: Under 8.5
- Confidence: 3/5
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Game Snapshot
- Matchup: Cleveland Guardians vs Chicago White Sox
- Date & Time: Friday, August 8, 2025, 7:40 p.m. ET
- Starting Pitchers:
- Guardians: Tanner Bibee (7-9, 4.51 ERA)
- White Sox: Aaron Civale (3-6, 3.99 ERA)
- Stadium: Rate Field, Chicago, IL
- Broadcast: CHSN and CLEG
Key Storylines
Pitching matchup
The big story in the pitching matchup in this game is that Aaron Civale will face his former team. Civale is just 3-6 this season but has a respectable 3.99 ERA. He will face Cleveland’s Tanner Bibee. Bibee is 7-9 and has a 4.51 ERA. It will be interesting to see how Civale’s familiarity with some Guardians hitters will impact the outcome of this game.
Key Players
- Cleveland: José Ramírez leads the Guardians with 23 home runs and a .296 batting average. He knows Civale’s pitching well and will try to take advantage of that.
- Chicago: Andrew Benintendi and Lenyn Sosa are both important components of the White Sox lineup. Benintendi leads the team with 14 home runs and Sosa leads them with a .277 batting average.
Recent team streaks
- The Guardians swept the New York Mets in their last series and they enter this game on a three-game winning streak.
- Chicago has lost four games in a row. They were swept over three games by the Seattle Mariners in their last series.
Best Player Props
| Player | Prop | Pick |
|---|---|---|
| José Ramírez | Home Runs | Over 0.5 |
| Andrew Benintendi | Total Bases | Over 1.5 |
| Tanner Bibee | Strikeouts | Over 5.5 |
Betting Trends & H2H
- The Guardians lead the season series against the White Sox 6-1 this season.
- Cleveland is 3-0 at home against the White Sox so far this year.
- The Guardians are 20-12 against AL Central opponents in 2025.
- Chicago is just 7-20 against their division rivals.
Guardians vs White Sox Model Projection
Score Projection: Guardians 5 – White Sox 2
Win Probability: Guardians 72%, White Sox 28%
Final Thoughts
The pitching matchup in this game isn’t terribly mismatched. But just about everything else about this game is a mismatch in favor of the Guardians. Cleveland’s lineup should have success against Civale and the Guardians should be able to win this game with some margin. I will lay the runline with Cleveland in this contest. I expect the Guardians to keep pace with the Tigers, who are expected to win on Friday night with Tarik Skubal on the mound.
