Cleveland Guardians vs Chicago White Sox Pick – 8/9/2025

The Cleveland Guardians won the first game of their three-game series against the Chicago White Sox on Friday night. Those two teams will play again on Saturday in a game with huge American League Wild Card implications. Before the Guardians and White Sox take the field in Chicago, keep reading to get my Guardians vs White Sox prediction for Saturday evening.

Our Guardians vs White Sox Pick

  • Pick: Cleveland Guardians ML
  • Confidence: ⭐⭐⭐⭐
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Game Snapshot

  • Matchup: Cleveland Guardians vs Chicago White Sox
  • Date & Time: Saturday, August 9, 2025, 7:10 p.m. ET
  • Starting Pitchers:
    • Guardians: Joey Cantillo
    • White Sox: Sean Burke
  • Stadium: Rate Field, Chicago, IL
  • Broadcast: CHSN and CLEG

Key Storylines

Pitching matchup

Cleveland hands the ball to Joey Cantillo. He is 2-2 and has posted a 4.37 ERA with 72 strikeouts over 55.2 innings this season. His strikeout numbers confirm that he has high-level stuff but his walk numbers confirm he lacks consistency. Sean Burke is 4-8 with a 4.23 ERA and over 100 innings pitched for the White Sox.

Key Players

  • Guardians: José Ramírez leads the offense with 23 homers and a .296 average.
  • White Sox: Luis Robert Jr. is electrifying and had a three-hit game against the Mariners a couple of days ago. Lenyn Sosa is a source of consistency from the bottom of the order.

Recent team streaks

  • The Guardians have won four games in a row coming into this matchup.
  • The White Sox have dropped five straight games.

Best Player Props

PlayerProp
José RamírezOver 0.5 Home Runs
Andrew BenintendiOver 1.5 Total Bases
Luis Robert Jr.Over 1.5 Total Bases
  • The Guardians lead the season series 7-1 over the White Sox.
  • Cleveland has won three straight games over Chicago.
  • The White Sox have allowed 8+ runs in four of their last five games.

Guardians vs White Sox Model Projection

Score Projection: Guardians 5 – White Sox 3
Win Probability: Guardians 60 %, White Sox 40 %

Final Thoughts

This is a huge game for the Cleveland Guardians. They are more than capable of catching up to the Wild Card teams in the AL if they can keep stacking up wins against inferior competition like the White Sox. In this game, I think that the Guardians will get another win over the White Sox. Cantillo can be erratic with his control at times. But I think he will keep the hitters of the White Sox off-balance and that should translate to a victory for the Guardians and a sixth straight loss for the White Sox.


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Home MLB Picks Cleveland Guardians vs Chicago White Sox Pick – 8/9/2025