Cleveland Guardians vs Chicago White Sox Pick – 8/10/2025

The Cleveland Guardians have dominated the Chicago White Sox during their current three-game weekend series. Cleveland has won both games in this series so far and they have covered the runline in both of those games. The Guardians will look to secure a three-game sweep with a win on Sunday. Before these AL Central rivals do battle again, continue reading to get my Guardians vs White Sox prediction.

Our Guardians vs White Sox Pick

  • Pick: Cleveland Guardians Moneyline
  • Confidence: 3/5
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Game Snapshot

  • Matchup: Cleveland Guardians vs Chicago White Sox
  • Date & Time: Sunday, August 10, 2025, 2:10 p.m. ET
  • Starting Pitchers: Slade Cecconi (5-4, 3.72 ERA) vs Davis Martin (3-9, 4.11 ERA)
  • Stadium: Rate Field, Chicago, IL
  • Broadcast: CHSN and CLEG

Key Storylines

Pitching matchup

Slade Cecconi brings consistency to this matchup for the Guardians with a 3.72 ERA and a 5-2 record on the season. His numbers compare favorably to Davis Martin’s 4.11 ERA and 3-9 record. Cecconi should give the Guardians the advantage on the mound in this game.

Key Players

  • Cleveland’s José Ramírez has been outstanding with a .293 average, .368 OBP, and .515 slugging percentage.
  • Other Guardians to watch include Steven Kwan and Kyle Manzardo contributing offensively.
  • Mike Tauchman and Colson Montgomery are among the most productive offensive threats for Chicago.

Recent team streaks

  • The Guardians have won five consecutive games.
  • The White Sox have lost six games in a row coming into Sunday’s series finale.

Best Player Props

PlayerStatProp
Colson MontgomeryHome RunsOver 0.5
Steven KwanTotal BasesOver 1.5
Slade CecconiStrikeoutsOver 5.5
  • The Guardians lead the season series 8-1 against the White Sox.
  • Cleveland is 22-12 against AL Central opponents this season. Most of that success has come against the White Sox.
  • Chicago is 7-22 against division opponents for the year.
  • Cleveland has won four straight games against the White Sox on the year.

Guardians vs White Sox Model Projection

Score Projection: Guardians 5 – White Sox 3

Win Probability: Guardians 57 %, White Sox 43 %

Final Thoughts

The Guardians enter Sunday’s game riding a wave of momentum. They have a more reliable starter in Slade Cecconi in this game and superior team performance metrics across most statistical categories. I expect the Guardians to complete a three-game sweep against the White Sox here. While I don’t mind the idea of laying the runline with Cleveland, I think the best bet for this matchup is to simply take the Guardians to win this game on the moneyline.


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Home MLB Picks Cleveland Guardians vs Chicago White Sox Pick – 8/10/2025