Cleveland Guardians vs Boston Red Sox Prediction – 9/3/2025
The Cleveland Guardians and Boston Red Sox will meet on Wednesday at Fenway Park in Boston. The Sox have won the first two games of this series and they will look to complete a three-game sweep at home. Cleveland’s recent struggles have sent them down the AL Wild Card standings and they will look to rebound here. Before the first pitch from Fenway, continue reading to get my Guardians vs Red Sox prediction.
Our Guardians vs Red Sox Pick
- Pick: Red Sox Moneyline
- Confidence: ★★★★☆
- Get Your Bonus Bets: Click the Claim Bonus button to get our DraftKings Sportsbook bonus – bet $5 and get $300 INSTANTLY and get over $200 off NFL Sunday Ticket!
Bet $5, Get $200 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $200 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Matchup: Cleveland Guardians vs Boston Red Sox
- Date & Time: Wednesday, September 3, 2025, 6:45 PM
- Starting Pitchers: Logan Allen (CLE) vs Brennan Bernardino (BOS)
- Stadium: Fenway Park, Boston, MA
- Broadcast: NESN, FDS Great Lakes
Key Storylines
Pitching Matchup
This game pits Logan Allen against Brennan Bernardino on the mound. Allen is the more established of the two pitchers opening this contest. He is 3-3 and has a 3.93 ERA for the year but has an experience edge in this matchup. Brennan Bernardino is 4-2 on the year with a 3.08 ERA for the Red Sox. He has allowed just one home run in 49.2 innings of work and keeping the ball in the park would be huge for him in this start.
Playoff Race
Boston is tied for the top spot in the AL Wild Card standings with the New York Yankees. Cleveland’s recent struggles have dropped them behind six other teams in the Wild Card race. The Guardians are four games back of the final Wild Card spot and will look for a big win to move closer in this game.
Recent Team Streaks
- Cleveland has lost three straight games to fellow AL Wild Card contenders Seattle and Boston.
- Boston has won three games in a row coming into this series finale.
Betting Trends & H2H
- The Red Sox have won four out of five games against the Guardians this year.
- Boston has won four in a row over Cleveland after losing their first matchup back in April.
Guardians vs Red Sox Model Projection
Score Projection: Red Sox 5 – Guardians 3
Win Probability: Red Sox 61%, Guardians 39%
Final Thoughts
Boston is simply playing better baseball than Cleveland right now. Bernardino has been pretty strong on the mound for the Sox as well and that should help them to get through the early innings without falling behind. Boston is 44-27 at home this year and I’ll take them to get a win at home to close out this three-game set.
