Cleveland Guardians vs Arizona Diamondbacks Prediction – 8/18/2025
The Cleveland Guardians will head West to take on the Arizona Diamondbacks on Monday night. Both teams are desperate to make up ground in their respective Wild Card races in this series and will try to set the tone in this series opener. Before these interleague opponents begin Monday’s matchup in Phoenix, continue reading to get my Guardians vs Diamondbacks prediction.
Our Guardians vs Diamondbacks Pick
- Pick: Guardians to win
- Confidence: 3/5
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Game Snapshot
- Matchup: Cleveland Guardians vs Arizona Diamondbacks
- Date & Time: Monday, August 18, 2025, 9:40 PM EDT
- Starting Pitchers:
- Guardians – Gavin Williams (7-4, 3.38 ERA)
- Diamondbacks – Zac Gallen (9-12, 5.31 ERA)
- Stadium: Chase Field, Phoenix, AZ
- Broadcast: MLB.tv
Key Storylines
Pitching matchup
Gavin Williams has pitched well for the Guardians in 2025. He has a winning record and a 3.38 ERA. He has struck out 127 batters over 128 innings. His recent performances include an eight-inning shutout against the Mets and quality starts against the Twins and Marlins. Diamondbacks starter Zac Gallen has struggled with a 9-12 record and a 5.31 ERA. His control has been shaky this year. Gallen has allowed 24 homers and 52 walks across 144 innings.
Key Players
- Guardians: José Ramírez leads the team with 25 homers, a .291 batting average, and 64 RBI. If he can find solid contact against Gallen it could lead to a Guardians win.
- Diamondbacks: Ketel Marte and Corbin Carroll make up the one-two punch for the Diamondbacks offensively.
Recent team streaks
- The Guardians have lost three games in a row and four of their last five entering this series.
- Arizona has also lost three straight games. Their three straight defeats came against the worst team in baseball in the Colorado Rockies.
Best Player Props
| Player | Prop |
|---|---|
| José Ramírez (CLE) | Over 1.5 Total Bases |
| Ketel Marte (ARI) | Over 0.5 RBI |
Betting Trends & H2H
- This is the first game of the season series between these teams this year.
- Cleveland is 32-29 on the road this season.
- Arizona is 30-30 in their home games this year.
Guardians vs Diamondbacks Model Projection
Score Projection: Cleveland Guardians 4 – Arizona Diamondbacks 3
Win Probability: Guardians 58%, Diamondbacks 42%
Final Thoughts
Neither of these clubs has been impressive of late. But one of them has to get a win to snap their three-game losing streak tonight. I will take the Guardians to be that team, thanks in large part to their advantage in the starting pitching department. Gallen’s lack of consistency will be a problem for Arizona again in this game and Cleveland should take full advantage of that tonight.
