Cincinnati Reds vs Los Angeles Angels Prediction – 8/20/2025
The Cincinnati Reds aim to extend their run of dominance against the Los Angeles Angels in the finale of their series on Wednesday. The Reds will face a challenging matchup against an All-Star pitcher here. They will need to find a way to still put runs on the board if they are going to complete a sweep on the road. Here, you can catch my breakdown of this interleague matchup and get my Reds vs Angels prediction for tonight.
Our Reds vs Angels Pick
- Pick: Angels Moneyline
- Confidence: ★★★★☆
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Game Snapshot
- Matchup: Cincinnati Reds vs Los Angeles Angels
- Date & Time: Wednesday, August 20, 2025, 9:38 PM ET
- Starting Pitchers: Nick Martinez (10–9, 4.73 ERA) vs Yusei Kikuchi (6–8, 3.52 ERA)
- Stadium: Angel Stadium, Anaheim, CA
- Broadcast: MLB Network
Key Storylines
Pitching Matchup
Nick Martinez takes the mound for the Reds with a 10–9 record and a 4.73 ERA. He will go up against Yusei Kikuchi of the Angels. Kikuchi enters this game with a 6–8 record and a 3.52 ERA. Kikuchi has been a consistent performer for the Angels and has the advantage in this matchup. But he will need to pitch his best to get the better of a potent Reds lineup.
Key Players
- Reds: Noelvi Marte hit a home run and knocked in a couple of runs for the Reds on Tuesday night. He will be a key player for the Reds in this contest.
- Angels: Jo Adell hit two home runs for the Angels last night and will try to give his team the upper hand tonight.
Recent Team Streaks
The Reds have won their last three games and they are just one game out of the final NL Wild Card spot. The Angels have been inconsistent. They have lost two straight games and four of their last five going into this series finale from Anaheim.
Best Player Props
| Player | Prop |
|---|---|
| Jo Adell | Over 1.5 Total Bases |
| Yusei Kikuchi | Over 5.5 Strikeouts |
Betting Trends & H2H
- The Reds are 2-0 against the Angels so far this season.
- Cincinnati is 25-16 against interleague opponents so far this season.
- The Angels are 20-18 against National League teams in 2025.
Reds vs Angels Model Projection
- Score Projection: Angels 5 – Reds 4
- Win Probability: Angels 55%, Reds 45%
Final Thoughts
The Reds have had the upper hand throughout this series against the Angels so far. But I think that the Angels will be able to salvage a game from this series. Kikuchi has been a consistently solid arm for Los Angeles and he should be able to keep the Reds at bay en route to a much-needed victory in front of their home crowd.
