Cincinnati Reds vs Arizona Diamondbacks Pick – 8/23/2025

The Cincinnati Reds and Arizona Diamondbacks will continue their weekend series in Phoenix on Saturday night. Arizona won a thrilling 11-inning game over Cincinnati on Friday and will look to build on that result in this game with huge NL Wild Card implications. Before the action begins from Arizona, you can find my Reds vs Diamondbacks prediction below.

Our Reds vs Diamondbacks Pick

  • Pick: Reds Moneyline
  • Confidence: 3/5
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Game Snapshot

  • Matchup: Cincinnati Reds vs Arizona Diamondbacks
  • Date & Time: Saturday, August 23, 2025, 8:10 PM ET
  • Starting Pitchers: Andrew Abbott (Reds) vs Nabil Crismatt (Diamondbacks)
  • Stadium: Chase Field, Phoenix, AZ
  • Broadcast: ARID (Arizona), FDSOH (Ohio)

Key Storylines

Pitching Matchup

Andrew Abbott has been dominant this season for the Reds. He comes into this game with an 8–3 record and a 2.28 ERA. His 199 ERA+ is the best in baseball this year. He has allowed one earned run or fewer in 15 of his 22 starts and has consistently delivered quality outings.

Nabil Crismatt of the Diamondbacks is making only his second start of the season. He pitched five innings and one run on three hits in his first start of the season. Crismatt lacks the extensive experience and consistency that Abbott brings to the mound. But he is more than capable of pulling off a shocking result here.

Key Players

  • Lourdes Gurriel Jr. drove in the first and last run of the night for the Diamondbacks on Friday. He had the walk-off RBI in the 11th inning for the D-Backs in Friday’s win and will look for more production on Saturday night.
  • Elly De La Cruz had two hits for the Reds on Friday and drove in the tying run in the eighth inning that sent the game to extra innings.

Recent Team Streaks

The Reds have dropped two games in a row and could really use a win to help their NL Wild Card hopes. Arizona has won three games in a row and are aiming to get a fourth straight victory at home tonight.

Best Player Props

PlayerProp
Andrew AbbottOver 5.5 strikeouts
Elly De La CruzOver 0.5 home runs
Geraldo PerdomoOver 1.5 total bases
  • Cincinnati leads the season series between these teams 3-1 despite Friday’s loss.
  • The home team is 4-0 in the games between these teams this season.
  • Cincinnati is 38-37 in night games this season.
  • Arizona is 40-44 in their night games for the year.

Reds vs Diamondbacks Model Projection

  • Score Projection: Reds 5 – Diamondbacks 3
  • Win Probability: Reds 56%, Diamondbacks 44%

Final Thoughts

The Diamondbacks have been playing well lately. But I think that the pitching matchup in this game will be too much for them to overcome. Andrew Abbott should have a strong performance for the Reds tonight and the Diamondbacks should struggle to overcome that with an inexperienced pitcher on the mound for them. I’ll take the Reds to win on the moneyline and to end the Diamondbacks’ current win streak.


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Home MLB Picks Cincinnati Reds vs Arizona Diamondbacks Pick – 8/23/2025