Chicago White Sox vs Tampa Bay Rays Pick – 7/23/2025

The Tampa Bay Rays are set to host the Chicago White Sox at George M. Steinbrenner Field on Wednesday night. These teams have split the first two games of this three-game set. The Rays enter the game as heavy favorites. But Chicago has already proven that they are capable of surprising Tampa in this series. Continue reading to get my White Sox vs Rays prediction for Wednesday night.

White Sox vs Rays Pick

• Pick: Tampa Bay Rays -1.5
• Confidence: ★★★★☆
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Game Snapshot

• Matchup: Chicago White Sox vs Tampa Bay Rays
• Date & Time: Wednesday, July 23, 2025, 7:35 PM ET
• Starting Pitchers: Jonathan Cannon (White Sox) vs Taj Bradley (Rays)
• Stadium: George M. Steinbrenner Field, Tampa, FL
• Broadcast: FDSN-SUN

Key Storylines

• Pitching Form: Jonathan Cannon is 4-7 and has a 4.18 ERA. He aims to build on his recent strong outing against the Pittsburgh Pirates. Cannon allowed one run over seven innings in that game. Taj Bradley is 6-6 with a 4.35 ERA. He threw six shutout innings against the Baltimore Orioles in his last start.
• Bullpen Usage: The Rays bullpen bounced back nicely on Tuesday after struggling to get White Sox hitters out on Monday night. How the Rays perform in relief in this game will be a big factor in determining the game’s outcome.
• Recent Team Streaks: The Rays have lost two of their last three games going into this one. The White Sox had a winning streak snapped with last night’s loss.

Best Player Props

Betting Trends & H2H

• The season series between these teams is tied 1-1 so far this year.
• After today, these teams play three more times in the month of September to finish their season series.
• The two games between these teams have gone 1-1 in the over/under market for the year.

White Sox vs Rays Model Projection

• Score Projection: White Sox 3 – Rays 5
• Win Probability: White Sox 35%, Rays 65%

Final Thoughts

There is not much value in betting on the Rays to win this game on the moneyline. But I will lay the runline with the Rays in this game instead. Tampa’s offense has not been all that impressive in this series so far. That should change in this game and I expect Bradley to pitch well for them to help them create separation in the first five innings or so.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.