Chicago White Sox vs Seattle Mariners Pick – 8/5/2025

The Seattle Mariners will host the Chicago White Sox at T-Mobile Park on Tuesday night. This is the first game of a three-game series between these American League opponents. Both teams had Monday off and will look to take advantage of that extra rest in this contest. For a full breakdown of this game, including my White Sox vs Mariners prediction, continue reading below.

Our White Sox vs Mariners Pick

• Pick: Mariners -1.5
• Confidence: ★★★★☆
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Game Snapshot

Key Storylines to Watch

• Pitching Matchup:

  • Bryan Woo (SEA): The Seattle right-hander has an 8-6 record with a 3.11 ERA and 127 strikeouts over 133 innings. Woo has been solid at home and has a 4-2 record with a 2.29 ERA in eight starts at T-Mobile Park.
  • Davis Martin (CWS): Chicago’s Davis Martin holds a 3-8 record with a 3.84 ERA. He’s struggled on the road with a 1-6 record and a 4.70 ERA in eight road starts.

• Team Momentum:

  • Mariners: Seattle has won three of their last four games coming into this contest.
  • White Sox: The White Sox had a three-game winning streak snapped in their last game against the Los Angeles Angels.

Best Player Props

Betting Trends & Head-to-Head

• The Mariners lead the season series over the White Sox 2-1.
• Two of the three games between these teams have been decided by one run.
• Two of the three games between Seattle and Chicago this season have gone under their respective totals.

White Sox vs Mariners Model Projection

Projected Score: Mariners 5 – White Sox 3
Win Probability: Mariners 69% | White Sox 31%

Final Thoughts

The White Sox enter this game at 20 games below .500 on the road for the year. Chicago also comes into this game at a disadvantage in the starting pitching department with All-Star Bryan Woo on the hill for Seattle. I will lay the runline with the Mariners in this game as I expect them to take a sizable lead early and not let that lead go.

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Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.

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