Chicago White Sox vs Pittsburgh Pirates Pick – 7/20/2025

The Chicago White Sox visit PNC Park on Sunday to face the Pittsburgh Pirates in the finale of their three-game series. Pittsburgh looks to stave off a sweep after dropping the first two games of this series to the team with the worst record in the American League. Here, I break down this matchup and give you my White Sox vs Pirates prediction for this matchup on Sunday afternoon.

Our White Sox vs Pirates Pick

• Pick: Pirates moneyline
• Confidence: ★★★☆☆
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Game Snapshot

• Matchup: Chicago White Sox at Pittsburgh Pirates
• Date & Time: Sunday, July 20, 2025, 1:35 p.m. ET
• Starting Pitchers: Andrew Heaney vs Aaron Civale
• Stadium: PNC Park, Pittsburgh, PA
• Broadcast: SportsNet PT, CHSN

Key Storylines

• Pitching form: Andrew Heaney has gone 4-8 with a 4.59 ERA for the Pirates this season. Chicago’s Aaron Civale has struggled through a tough season with a 1-6 record and a 5.30 ERA.
• Bullpen usage: Pittsburgh has struggled to get outs from its relievers in this series so far. The White Sox have lit up Pittsburgh pitching over the first two games and the Pittsburgh pen will have to be better if they want to salvage this game on Sunday.
• Recent team streaks: The White Sox have surged with consecutive blowout wins. The Pirates have lost two in a row at home and have dropped four of their last five games overall.

Best Player Props

Betting Trends & H2H

• The White Sox are 2-0 against the Pirates so far this season.
• Both games in the season series between these teams have gone over the total.
• Chicago is outscoring the Pirates 20-5 in their two meetings this year.

White Sox vs Pirates Model Projection

Score Projection: Pirates 5 – White Sox 4

Win Probability: Pirates 60%, White Sox 40%

Final Thoughts

The White Sox have dominated the Pirates in this series so far. But I expect that to change in this series finale from PNC Park. The Pirates have the advantage in the starting pitching department going into this game. And while the Pirates bullpen has struggled to get outs in this series, I think they will do enough to help the Pirates get into the win column to close out this three-game set.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.