Chicago White Sox vs Minnesota Twins Prediction – 9/4/2025

The Chicago White Sox and Minnesota Twins will close out a four-game series on Thursday night in Minneapolis. The White Sox have won the first three games of this series and are one win away from completing a shocking four-game sweep. Before the final game of this series begins, continue reading to get my White Sox vs Twins prediction.

Our White Sox vs Twins Pick

  • Pick: Minnesota Twins to win
  • Confidence: 3/5
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Game Snapshot

  • Matchup: Chicago White Sox vs Minnesota Twins
  • Date & Time: Thursday, September 4, 2025, 7:40 p.m. ET
  • Starting Pitchers:
    • White Sox – Fraser Ellard (0-2, 4.82 ERA)
    • Twins – Taj Bradley (6-7, 4.82 ERA)
  • Stadium: Target Field, Minneapolis, MN
  • Broadcast: TV: MNNT and CHSN

Key Storylines

Pitching matchup

Fraser Ellard has limited MLB experience. He has thrown just 9.1 innings with decent control but no wins to date. Taj Bradley has been inconsistent but has a huge edge in terms of experience going into this game. His ability to generate strikeouts is a weapon but his ERA and WHIP are high going into this game.

Key Players

  • Byron Buxton (Twins): Buxton is batting .273 with 29 home runs and 72 RBI. He is riding a seven-game hitting streak and has 10 RBI in his last 10 games.
  • Andrew Benintendi (White Sox): Benintendi is coming off a four-hit game and has provided some spark for Chicago’s offense.
  • Lenyn Sosa (White Sox): Sosa is leading the team with 19 home runs and a .265 average.

Recent Team Streaks

  • White Sox: The White Sox are winners of their last four games.
  • Twins: Minnesota is slumping at 3-7 in their last 10 games. They have lost three straight games coming into this contest.

Best Player Props

PlayerProp
Byron Buxton1+ Home Runs
Taj BradleyOver 5.5 Strikeouts
Andrew BenintendiUnder 1.5 Total Bases
  • Chicago is 7-5 this season against Minnesota.
  • Chicago has won the last five games between these teams.
  • Chicago is 22-46 on the road for the season.
  • Minnesota has a 35-35 record at home for the year.

White Sox vs Twins Model Projection

Score Projection: Twins 6 – White Sox 5

Win Probability: Twins 52%, White Sox 48%

Final Thoughts

The Twins are favorites in this game despite struggling consistently in this series. While Chicago has certainly had the upper hand in this matchup over the last couple of months, I am still compelled to go with the Twins to win this contest and save themselves from the embarrassment of being swept over four games by one of the worst teams in baseball.


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Home MLB Picks Chicago White Sox vs Minnesota Twins Prediction – 9/4/2025