Chicago Cubs vs San Francisco Giants Prediction – 8/27/2025
The Chicago Cubs and San Francisco Giants will meet in the second game of their three-game series on Wednesday night. San Francisco got the win in the opening game of the series and they will look to keep winning to improve their chances of catching up in the NL Wild Card chase. Before the first pitch from Oracle Park, continue reading to get my Cubs vs Giants prediction.
Our Cubs vs Giants Pick
- Pick: Chicago Cubs Moneyline
- Confidence: 4/5
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Game Snapshot
- Matchup: Chicago Cubs vs San Francisco Giants
- Date & Time: Wednesday, August 27, 2025, 9:45 PM ET
- Starting Pitchers: Colin Rea (Cubs) vs Carson Whisenhunt (Giants)
- Stadium: Oracle Park, San Francisco, CA
- Broadcast: NBC Sports Bay Area and Marquee Sports Network
Key Storylines
Pitching Matchup
Colin Rea enters this game at 10-5 with a 3.96 ERA and he takes the mound for the Cubs tonight. Rea has been a reliable starter this season and helped the Cubs to beat the Milwaukee Brewers in his last start. His ability to limit walks and manage traffic on the bases will be important against a Giants lineup that has struggled offensively.
Carson Whisenhunt will get the start for the Giants tonight. He is 1-1 and has a 4.91 ERA for the season. Whisenhunt has shown flashes of potential but has been prone to giving up runs. The Cubs’ potent offense will look to exploit his inexperience and capitalize on scoring opportunities.
Recent Team Streaks
The Cubs had a three-game winning streak snapped on Tuesday night when they lost 5-2 to the Giants. The Giants have won three games in a row coming into this contest and will look to keep winning to help themselves in the NL Wild Card race. The Giants are seven games back of the final NL Wild Card spot going into Wednesday’s action and they are running out of time to qualify for the playoffs.
Best Player Props
| Player | Prop |
|---|---|
| Pete Crow-Armstrong | Over 0.5 Home Runs |
| Seiya Suzuki | Over 1.5 Total Bases |
| Carson Whisenhunt | Under 4.5 Strikeouts |
| Rafael Devers | Under 1.5 Total Bases |
Betting Trends & H2H
- The Giants hold a 3-1 lead over the Cubs in their season series this year.
- All four games between Chicago and San Francisco this season have been decided by two runs or more.
- The Cubs have a 35-31 record on the road for the season.
- San Francisco is 31-33 on their home field during the 2025 season.
Cubs vs Giants Model Projection
- Score Projection: Cubs 5 – Giants 4
- Win Probability: Cubs 51%, Giants 49%
Final Thoughts
Colin Rea gives the Cubs a starting pitching advantage against the Giants going into tonight’s game. The Cubs also have a higher upside on offense and those things should add up to a win for the Giants on the road. The Giants need wins to catch up in the Wild Card race but they aren’t going to get one here.
