Chicago Cubs vs Chicago White Sox Prediction – 7/26/2025
The Chicago White Sox and Chicago Cubs will continue their crosstown rivalry on Saturday night at Rate Field. The White Sox opened this series with a win thanks to a strong offensive showing. They will look to upset the Cubs for the second straight night in this matchup. Continue reading to get my breakdown of this game, including my Cubs vs White Sox prediction.
Our Cubs vs White Sox Pick
- Pick: Chicago Cubs -1.5
- Confidence: ★★★★☆
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Game Snapshot
- Matchup: Chicago Cubs vs Chicago White Sox
- Date & Time: Saturday, July 26, 2025, 7:10 p.m. ET
- Starting Pitchers:
- Cubs – Cade Horton (3‑3, 4.04 ERA)
- White Sox – Aaron Civale (2‑6, 4.76 ERA)
- Stadium: Rate Field, Chicago, IL
- Broadcast: CHSN and MARQ
Key Storylines
- The Cubs enter at 60‑43 and are heavy favorites in this contest. But they did stumble against the White Sox last night. The Cubbies gave up 12 runs in that game and will look to turn things around here.
- The White Sox have enjoyed an offensive explosion over hte last couple of games. They have scored a total of 23 runs in their last two outings and will try to sustain a similar level of production here.
- Cade Horton takes the ball for the Cubs tonight. He is 3-3 with a 4.04 ERA.
- Aaron Civale gets the nod for the Sox tonight. He has a 2‑6 record and a 4.76 ERA in what has been a disappointing season for him.
- The White Sox have won four of their last five games. The Cubs have lost four of their last five. Given what we have seen from these teams this year, you’d expect those numbers to be reversed.
Best Player Props
| Player | Prop |
|---|---|
| Pete Crow‑Armstrong | Over 1.5 total bases |
| Seiya Suzuki | Over 0.5 home runs |
| Miguel Vargas | Over 0.5 home runs |
Betting Trends & H2H
- The Cubs lead the season series 3-1 over the White Sox.
- The over has hit in three of the four games between these teams this season.
- Chicago has given up eight runs or more in three of their last four games.
Cubs vs White Sox Model Projection
Score Projection: Cubs 6 – White Sox 4
Win Probability: Cubs 65%, White Sox 35%
Final Thoughts
This game seems like the perfect opportunity for the Cubs to get back on track after a rough stretch of results. The Cubbies have the starting pitching advantage in this game and are more solid in their bullpen as well. I expect the offensive firepower of the Cubs to shine through in this game and for their pitching staff to finally stop giving up so many runs. I’ll back the Cubs to cover the runline as a favorite.
