Boston Red Sox vs Chicago Cubs Pick – 7/19/2025

The Chicago Cubs and Boston Red Sox square off on Saturday in the second game of their three-game set at Wrigley Field. The Red Sox had their 10-game winning streak snapped by Chicago on Friday. They will look to bounce back here and help their chances in the American League playoff chase. Here, we break down this interleague matchup and bring you our Red Sox vs Cubs prediction for tonight.

Our Red Sox vs Cubs Pick

• Pick: Chicago Cubs Moneyline
• Confidence: ★★★★☆
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Game Snapshot

• Matchup: Boston Red Sox vs Chicago Cubs
• Date & Time: Saturday, July 19, 2025 at 7:15 PM EDT
• Starting Pitchers: Brayan Bello vs Shōta Imanaga
• Stadium: Wrigley Field, Chicago, IL
• Broadcast: FOX

Key Storylines

• Pitching form: Brayan Bello is 6-3 on the year and has a 3.14 ERA. He has allowed two earned runs or fewer in his last three starts and will look to continue rolling in this contest. Shōta Imanaga has a 6-3 record and a 2.65 ERA. He gave up just one earned run in seven innings of work against the New York Yankees in his last start.
• Bullpen usage: Both bullpens have been spectacular so far this year. Chicago’s was slightly better last night and they will look for a repeat performance in tonight’s game.
• Recent team streaks: Boston’s 10-game win streak came to an end in Friday’s loss. Chicago has won three straight and four of their last five games.

Best Player Props

Betting Trends & H2H

• The Cubs hold a 1-0 lead in the season series after Friday’s 4-1 win over Boston.
• Chicago has allowed four total runs over their last three games.
• The under has hit in three straight games that the Red Sox have played in.

Boston Red Sox vs Chicago Cubs Model Projection

Score Projection: Boston 3 – Chicago 5

Win Probability: Boston 39%, Chicago 61%

Final Thoughts

Both pitchers in this contest have been performing well of late. But I give the edge to Imanaga and the Cubs in this game. Imanaga has held opposing batters under a .200 average for the season. Even if the Red Sox hit better than that tonight, I don’t expect them to do enough to do serious damage against the Cubs’ starting pitcher. Look for the Cubs to move to 2-0 against the Sox in this series with a win.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.