Boston Red Sox vs Baltimore Orioles Pick – 8/26/2025

The Boston Red Sox picked up a win in the opening game of their four-game series against the Baltimore Orioles. They will look for a repeat performance on Tuesday night in another huge game in the American League Wild Card race. Boston will face a starting pitcher who is making his return to the diamond for the Orioles in this game. Before the action begins in Baltimore, continue reading to get my Red Sox vs Orioles prediction.

Our Red Sox vs Orioles Pick

  • Pick: Boston Red Sox Moneyline
  • Confidence: 3/5
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Game Snapshot

  • Matchup: Boston Red Sox (72-60) vs Baltimore Orioles (60-71)
  • Date & Time: Tuesday, August 26, 2025, 6:35 p.m. ET
  • Starting Pitchers: Lucas Giolito (8-2, 3.72 ERA) vs Kyle Bradish (first start of season)
  • Stadium: Oriole Park at Camden Yards, Baltimore, MD
  • Broadcast: MASN and NESN

Key Storylines

Pitching matchup

Lucas Giolito has been a reliable option for Boston this season with an 8-2 record and a 3.72 ERA. He has limited free passes while delivering a steady strikeout rate. Boston has had a ton of success winning games with Giolito on the mound and they will look for another win behind him tonight. Kyle Bradish is stepping in for his first start of the season. It will be interesting to see how he performs coming off the IL for this contest.

Key Players

  • Boston: Jarren Duran hit a three-run home run to put the Red Sox ahead for good on Monday night.
  • Baltimore: Colton Cowser drove in all three runs for the Orioles in their loss on Monday and he will look to make another big impact in this contest.

Recent team streaks

  • Boston has won four of its last five games and they are at the top of the American League Wild Card standings.
  • Baltimore has lost four of its last five games and their only win during that span came when Trevor Rogers was on the mound against Houston.

Best Player Props

PlayerProp
Wilyer AbreuOver 1.5 Total Bases
Trevor StoryOver 0.5 Home Runs
Gunnar HendersonOver 1.5 Total Bases
  • The season series between these teams is tied 5-5 going into Tuesday’s game.
  • Boston’s win on Monday snapped a four-game winning streak for the Orioles over the Red Sox.

Red Sox vs Orioles Model Projection

  • Score Projection: Boston Red Sox 5 – Baltimore Orioles 4
  • Win Probability: Red Sox 53%, Orioles 47%

Final Thoughts

It will be very interesting to see what we get from Kyle Bradish on the mound in this contest. Bradish has a high ceiling when he’s healthy but we don’t know how ready he is to take on a major league workload just yet. Giolito and the Red Sox are the safer bet at this point in time and I will take Boston to come away with a second straight road win over their division rivals.


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Home MLB Picks Boston Red Sox vs Baltimore Orioles Pick – 8/26/2025