Baltimore Orioles vs Toronto Blue Jays Pick – 3/27/2025

The Baltimore Orioles and Toronto Blue Jays are set to kick off their 2025 MLB season with an exciting matchup at Rogers Centre on Thursday, March 27, at 3:07 p.m. ET. This Opening Day game features two American League East rivals aiming to start their campaigns on a positive note.

Baltimore Orioles vs. Toronto Blue Jays Game Preview

The Orioles enter the season following a strong 91-71 record in 2024, which earned them a postseason berth. However, their playoff run was short-lived as they were swept in the Wild Card round by the Kansas City Royals. Baltimore aims to build upon last year's success and make a deeper postseason push this season.

Conversely, the Blue Jays concluded the 2024 season with a disappointing 74-88 record, finishing last in the AL East. Determined to reverse their fortunes, Toronto looks to leverage their home-field advantage and set a winning tone early in the season.

On the mound for the Orioles is right-hander Zach Eflin. During Spring Training, Eflin appeared in four games, posting an 0-1 record with a 5.40 ERA and nine strikeouts over 11.2 innings. Opposing him for the Blue Jays is right-hander José Berríos, who had an impressive Spring Training, recording a 2-0 record with a 2.18 ERA and 18 strikeouts across 20.2 innings.

Offensively, the Orioles will rely on key contributors such as Ryan Mountcastle, who led the team with five home runs during Spring Training, and Jackson Holliday, who posted a .333 batting average (16-for-48) in the same period. For the Blue Jays, Bo Bichette stood out with a .373 average during Spring Training, while Vladimir Guerrero Jr. hit .298, showcasing his consistent offensive prowess.

Betting Insights

As of Wednesday, the betting odds for this matchup are as follows:

• Moneyline: Baltimore Orioles (-115), Toronto Blue Jays (-105)
• Spread: Orioles -1.5 (+145), Blue Jays +1.5 (-175)
• Total: 8.5 runs

These odds suggest a closely contested game, with the Orioles being slight favorites. Bettors should consider the following trends and insights:

• The Orioles had a 67-52 record as moneyline favorites last season, winning 56.3% of those games.
• Baltimore performed well after losses, with a 79-52 record in such situations since the 2023 season, indicating resilience.
• The Blue Jays struggled as underdogs last season, with a 27-52 record, winning only 34.2% of those games.
• Toronto had a strong Spring Training in 2025, finishing with an 18-10 record, which could indicate improved performance heading into the regular season.

Baltimore Orioles vs. Toronto Blue Jays Prediction

Considering the available information, this Opening Day matchup appears to be evenly matched. The Orioles' strong performance last season and the Blue Jays' impressive Spring Training suggest both teams have the potential to secure a victory.

Given the pitching matchup, with Berríos showcasing better form during Spring Training compared to Eflin, and the Blue Jays' home-field advantage, Toronto may have a slight edge in this contest. Additionally, the Blue Jays' offensive leaders, such as Bichette and Guerrero Jr., have demonstrated consistency that could prove pivotal.

Therefore, the prediction leans towards a narrow victory for the Toronto Blue Jays, with the total runs potentially exceeding 8.5, considering the offensive capabilities of both teams.

As always, bettors should conduct thorough research and consider all factors before placing wagers. Baseball games can be unpredictable, and various elements can influence the outcome on any given day.

For more on today's game check out the comprehensive statistics, betting odds, and trends below. Be sure to check out all our free MLB picks here.