Baltimore Orioles vs Cleveland Guardians Pick – 7/23/2025
The Cleveland Guardians are slight favorites against the Baltimore Orioles at Progressive Field on Wednesday night. The Guardians have won the first two games of this four-game series and will look to secure a third straight win here. Continue scrolling to get my analysis for this American League matchup, including my Orioles vs Guardians prediction for tonight’s game. Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+ Gambling Problem? Call or TEXT 1-800-Gambler 21+ I am very interested to see how Zach Eflin looks in his return from the IL. But based on his numbers so far this season there is cause for concern there. I will take the Guardians in this game, as they should take advantage of Eflin’s struggles as he gets back into the swing of things. Cleveland will go into Thursday with a chance to complete a four-game sweep.Our Orioles vs Guardians Pick
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Key Storylines
Best Player Props
Player Prop Jose Ramirez Over 0.5 Home Runs Ramon Laureano Over 0.5 Home Runs Slade Cecconi Over 5.5 Strikeouts Betting Trends & H2H
Orioles vs Guardians Model Projection
Final Thoughts
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ATS.io features affiliate links to licensed online casinos, sportsbooks, and gambling platforms. That means if you click on them and end up signing up or making a deposit, we might earn a commission at no extra cost to you. We only work with licensed and reputable online casinos, social casinos and sportsbooks. Our content whether it’s reviews, guides, or betting tips is written with the goal of being honest, helpful, and based on real experience. While we do earn through affiliate partnerships, it doesn’t affect our recommendations. If a site isn’t safe or doesn’t meet our standards, we won’t promote it. Simple as that. We also take responsible gambling seriously. We encourage all our readers to gamble safely, set limits, and know when to take a break. Have questions? Feel free to reach out. We’re always happy to chat.
