Baltimore Orioles vs Chicago Cubs Prediction – 8/2/2025

The Baltimore Orioles and Chicago Cubs will meet on Saturday afternoon in the second game of their weekend series. Chicago won a low-scoring game on Friday night to open this series up. They will look for a second straight win at home over the Orioles here. Before the action begins at Wrigley Field, you can continue reading to get my Orioles vs Cubs prediction.

Our Orioles vs Cubs Pick

  • Pick: Cubs -1.5
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: Baltimore Orioles vs Chicago Cubs
  • Date & Time: Saturday, August 2, 2025, 2:20 p.m. ET
  • Starting Pitchers: Tomoyuki Sugano vs Matthew Boyd
  • Stadium: Wrigley Field, Chicago, IL
  • Broadcast: Fox Sports 1

Key Storylines

Pitching matchup

The Orioles will send Tomoyuki Sugano to the mound in this game. He enters with an 8‑5 record and 4.38 earned run average. Sugano most recently earned a win against Colorado, allowing one run over six innings and striking out eight. The Cubs will counter with southpaw Matthew Boyd. Boyd is 11‑4 with a sparkling 2.47 ERA. His ability to suppress runs will make it tough for Baltimore’s middling offense to thrive.

Key Players

  • Gunnar Henderson (Orioles): .283 batting average, .813 OPS. He continues to be their most consistent impact bat deadline.
  • Pete Crow-Armstrong (Cubs): PCA has hit for a decent average and with a ton of power. He will be key to the success of the Cubs here.

Recent team streaks

The Orioles have lost two games in a row coming into this matchup. Chicago has won two straight games. That includes their 1-0 win over the Orioles on Friday.

Best Player Props

PlayerPropPick
Tomoyuki SuganoStrikeoutsUnder 4.5
Gunnar HendersonTotal BasesOver 1.5
Pete Crow-ArmstrongHome RunsOver 0.5
  • The Cubs have allowed just three runs over their last two games.
  • Baltimore is 24-25 in day games this season.
  • Chicago is 29-21 in day games.
  • Chicago is 1-0 over the Orioles so far this season.

Orioles vs Cubs Model Projection

Score Projection: Cubs 6 – Orioles 4

Win Probability: Cubs 57%, Orioles 43%

Final Thoughts

Chicago has a pretty clear edge in this game. While Sugano is certainly not a bad pitcher, I don’t think he stacks up well with Boyd of Chicago. And when you add in the fact that the Cubs are far more consistent offensively, I think that Chicago should win with some margin on Saturday afternoon. I will lay the runline with the Cubbies here, as they should continue to impose their will at Wrigley.


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Home MLB Picks Baltimore Orioles vs Chicago Cubs Prediction – 8/2/2025