Arizona Diamondbacks vs Milwaukee Brewers Prediction – 8/27/2025
The Arizona Diamondbacks have struggled against the Milwaukee Brewers in their series this week. The Brewers have taken the first two games of this four-game set and are favorites to win again tonight. Arizona will send one of their best pitchers to the mound for this game. But will that be enough to derail the red-hot Brewers? Continue reading to get my thoughts and to get my Diamondbacks vs Brewers prediction.
Our Diamondbacks vs Brewers Pick
- Pick: Milwaukee Brewers to win
- Confidence: 4/5
- Claim Your Bonus Bets: Click the Claim Bonus button below to claim our DraftKings Sportsbook bonus. You can bet $5 and get $300 in bonus bets INSTANTLY and over $200 off NFL Sunday Ticket!
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Matchup: Arizona Diamondbacks vs Milwaukee Brewers
- Date & Time: Wednesday, August 27, 2025, 7:40 p.m. ET
- Starting Pitchers: Quinn Priester (11-2, 3.44 ERA) vs Ryne Nelson (6-3, 3.63 ERA)
- Stadium: American Family Field, Milwaukee, WI
- Broadcast: FDSWI and ARID
Key Storylines
Pitching matchup
We are set for a very good pitching matchup in this game. Milwaukee’s Quinn Priester enters with an 11-2 record and a 3.44 ERA. Priester exceeding expectations this year is a big reason that the Brewers have the best record in baseball. Arizona’s Ryne Nelson has a commendable 3.63 ERA across 17 starts. Both pitchers have above-average metrics and this game could come down to which starter is at their best tonight.
Key Players
Both bullpens are going to be key in this game for different reasons. The Diamondbacks had to get their bullpen involved early in last night’s loss after Brandon Pfaadt was roughed up early. That extra workload could make tonight’s game tougher on them. Milwaukee’s bullpen gave up five runs on Tuesday and has to be better tonight.
Recent team streaks
- The Diamondbacks are entering this game on a three-game losing streak.
- Milwaukee has won two games in a row and they have a commanding lead in the NL Central standings.
Best Player Props
| Player | Category | Prop |
|---|---|---|
| Christian Yelich | Home Runs | Over 0.5 |
| Quinn Priester | Strikeouts | Over 5.5 |
| Ketel Marte | Total Bases | Over 1.5 |
Betting Trends & H2H
- Milwaukee leads the season series over the Diamondbacks 3-2.
- Home teams are 4-1 in the games played between these teams in 2025.
- Arizona is 30-37 on the road for the year after their road loss on Tuesday.
- The Brewers improved to 45-22 at home with their walk-off win last night.
- The first two games of this four-game series have gone over their respective totals. Both games have had 12 runs or more scored.
Diamondbacks vs Brewers Model Projection
Score Projection: Brewers 5 – Diamondbacks 3
Win Probability: Brewers 59%, Diamondbacks 41%
Final Thoughts
We should see a lower-scoring game from these teams than we have in the first two games of this series. Both starting pitchers have looked good this year but I think that Priester has been just a bit better than Nelson throughout the season. The best team in baseball right now is the Milwaukee Brewers and they should get another victory at home tonight.
