Arizona Diamondbacks vs Milwaukee Brewers Pick – 8/25/2025

The Milwaukee Brewers will host the Arizona Diamondbacks on Monday night at American Family Field in Milwaukee. The Brewers have the best record in baseball and will look to continue their winning ways here against a desperate Diamondbacks team. Before the action begins in Milwaukee, continue reading to get my Diamondbacks vs Brewers prediction.

Our Diamondbacks vs Brewers Pick

  • Pick: Brewers -1.5
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: Arizona Diamondbacks vs Milwaukee Brewers
  • Date & Time: Monday, August 25, 2025, 7:40 p.m. ET
  • Starting Pitchers:
    • Milwaukee – Brandon Woodruff (4-1, 2.47 ERA)
    • Arizona – Eduardo Rodríguez (5-7, 5.40 ERA)
  • Stadium: American Family Field, Milwaukee, WI
  • Broadcast: FDSWI and ARID

Key Storylines

Pitching matchup

Brandon Woodruff has been elite this season with a pristine 2.47 ERA and 55 strikeouts over 43.2 innings. As long as he can continue to stay healthy for the Brewers they will continue to be a threat to win the World Series. Eduardo Rodríguez’s numbers have been shaky with a 5.40 ERA in 2025 and a 4.65 FIP. He does hold a career 2.60 ERA in his few starts against Milwaukee. But the Brewers have the edge in the starting pitching department here.

Recent team streaks

  • The Diamondbacks had a long winning streak snapped in their final game against the Cincinnati Reds on Sunday.
  • The Brewers have lost two games in a row but they are still atop the National League standings.

Best Player Props

PlayerProp
Corbin Carroll (ARI)Under 1.5 Total Bases
William Contreras (MIL)Over 1.5 Total Bases
Christian Yelich (MIL)Over 0.5 Home Runs
  • The Diamondbacks lead the season series 2-1 over the Brewers this year.
  • This will be the first game between these teams played in Milwaukee for the season.
  • The Diamondbacks are 41-44 in night games this season.
  • Milwaukee is 46-27 at home for the year.

Diamondbacks vs Brewers Model Projection

Score Projection: Brewers 4 – Diamondbacks 3
Win Probability: Brewers 67%, Diamondbacks 33%

Final Thoughts

The Milwaukee Brewers have been the best team in baseball in the second half of the season and they should continue rolling in this contest. Woodruff has been pitching at an elite level since coming back from injury. Against a pitcher in Rodriguez who has been a disappointment this year, Woodruff should be able to deliver his team to a win in front of his home crowd. I’ll lay the runline with the Brew Crew in tonight’s game.


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Home MLB Picks Arizona Diamondbacks vs Milwaukee Brewers Pick – 8/25/2025