Arizona Diamondbacks vs Detroit Tigers Prediction – 7/30/2025
The Detroit Tigers are set to host the Arizona Diamondbacks on Wednesday at Comerica Park. The Tigers have dominated this series so far and will look to complete a three-game sweep with a win here. They will look to do so with a newly acquired pitcher on the mound. Here, I break down this interleague matchup and bring you my Diamondbacks vs Tigers prediction for this matinee from Detroit.
Our Diamondbacks vs Tigers Pick
- Pick: Arizona Diamondbacks Moneyline
- Confidence: ★★★★☆
- Get Your Bonus Bets: Click the Claim Bonus button below and sign up with bet365 bonus code ATSBONUS to bet $5 and win $150 in bonus bets win or lose!


Game Snapshot
Matchup | Detroit Tigers vs. Arizona Diamondbacks |
Date & Time | July 30, 2025, 1:10 PM ET |
Starting Pitchers | Chris Paddack (DET) vs. Ryne Nelson (ARI) |
Stadium | Comerica Park, Detroit, MI |
Broadcast | MLB Network |
Key Storylines to Watch
Pitching Form: The Tigers will go with Chris Paddack on the mound to start this game. Paddack was acquired from the Minnesota Twins and is making his first start with the Tigers. He has had an ERA of 6.00 or higher in both June and July and will hope that a change of scenery does him good. Paddack will go up against Arizona’s Ryne Nelson. Nelson is 6-2 with a 3.29 ERA. He has not lost a start since June 7.
Bullpen Usage: The Tigers’ bullpen has had the advantage in this series so far. They have helped hold the Diamondbacks to just three total runs through the first two games of this series. Arizona’s struggling bullpen has been leaking runs left and right against the Tigers.
Trade Deadline: The MLB trade deadline is looming and there are major implications for this game. The deadline is on Thursday and Arizona’s Eugenio Suarez is one of the top targets available in the trade market this year. He is day-to-day with a hand injury and we might not see him play in a Diamondbacks uniform again.
Best Player Props
Player | Prop | Pick |
---|---|---|
Ryne Nelson | Strikeouts | Over 5.5 |
Riley Greene | Total Bases | Over 1.5 |
Ketel Marte | Hits | Over 0.5 |
Betting Trends & Head-to-Head
- The Tigers lead the season series between these teams 2-0.
- This is the last time this season that the Tigers and Diamondbacks will meet, barring them both reaching the World Series.
- The over/under has been split 1-1 in the two games these teams have played.
- Arizona has lost four straight games coming into this matchup.
- The Tigers have won three games in a row
Diamondbacks vs Tigers Model Projection
Projected Score: Diamondbacks 5 – Tigers 3
Win Probability: Diamondbacks 51%, Tigers 49%
Final Thoughts
I’m just not sure that Chris Paddack is the answer that the Tigers needed in the trade market. Paddack has been struggling mightily going into his first start with his new team. And while Detroit’s lineup is dangerous, I think that we see a solid showing from Ryne Nelson today. I will take the Diamondbacks as a slight underdog, even if we don’t see Suarez due to his injured hand.