Arizona Diamondbacks vs Detroit Tigers Prediction – 7/28/2025

The Detroit Tigers will host the Arizona Diamondbacks at Comerica Park in Detroit on Monday night. Detroit has one of the best records in the American League but they have struggled of late. They will look to turn things back in the right direction with a win in the first game of this series. Before the Diamondbacks and Tigers square off, continue reading to get my Tigers vs Diamondbacks prediction.

Our Diamondbacks vs Tigers Pick

  • Pick: Diamondbacks moneyline
  • Confidence: ★★★★☆
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Game Snapshot

  • Matchup: Detroit Tigers vs Arizona Diamondbacks
  • Date & Time: Monday, July 28, 2025, 6:40 p.m. ET
  • Starting Pitchers: Troy Melton (DET) vs Eduardo Rodríguez (ARI)
  • Stadium: Comerica Park, Detroit, MI
  • Broadcast: FDSDET and ARID

Key Storylines

Pitching matchup

Detroit turns to rookie Troy Melton to start this game. Melton has only pitched five innings in MLB and has a 10.80 ERA. He will look to rebound from some early struggles in this game at home. Arizona counters with Eduardo Rodríguez in this game. Rodriguez is a former Tiger who is struggling this year. He is 3-6 with a 5.50 ERA and will look to reclaim his old form at a familiar venue.

Key Players

Detroit leans on Riley Greene offensively. Greene leads the club with 25 home runs and 81 RBI so far this year. The Tigers will also rely on Spencer Torkelson and Gleyber Torres to supply additional power. Arizona features All‑Star third baseman Eugenio Suárez for now. Suarez has hit 36 home runs and has 87 RBI to lead the team. But he might not be in Arizona for long as he has been involved in trade rumors.

Recent team streaks

Detroit is enduring a rough patch. They have lost eight of their last 10 games and have lost four of their last five contests. Arizona has lost four of their last five games but did salvage the final game of their four-game series against the Toronto Blue Jays before this series.

Best Player Props

PlayerProp Type
Riley Greene (DET)1+ Home Runs
Spencer Torkelson (DET)Over 1.5 Total Bases
Eugenio Suárez (ARI)1+ Home Runs
Eduardo Rodríguez (ARI)Over 4.5 Strikeouts
  • This is the first game of the regular season series between the Tigers and Diamondbacks.
  • There are three games scheduled in this series. Those are the only games of this year between these teams.
  • Detroit is 33-21 at home this year. Arizona is 25-27 on the road.

Diamondbacks vs Tigers Model Projection

Score Projection: Diamondbacks 5 – Tigers 4

Win Probability: Diamondbacks 54%, Tigers 46%

Final Thoughts

The Tigers have a better record than the Diamondbacks this season. But Detroit is struggling mightily heading into this game. Combine that with the Diamondbacks having a starting pitching edge and I’ll go with Arizona to come away with a win on the road to open this three-game set.


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Home MLB Picks Arizona Diamondbacks vs Detroit Tigers Prediction – 7/28/2025