Arizona Diamondbacks vs Detroit Tigers Pick – 7/29/2025

The Detroit Tigers are set to host the Arizona Diamondbacks on Tuesday night at Comerica Park. The Tigers got a much-needed win in the opening game of this series at home. They will look for a repeat performance against a Diamondbacks team that is struggling of late. Before first pitch in Detroit, continue reading to get my Diamondbacks vs Tigers prediction.


Our Diamondbacks vs Tigers Pick

  • Pick: Detroit Tigers -1.5
  • Confidence: ★★★★☆
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Game Snapshot

MatchupArizona Diamondbacks vs. Detroit Tigers
Date & TimeJuly 29, 2025, 6:40 PM EDT
Starting PitchersBrandon Pfaadt vs. Casey Mize
StadiumComerica Park, Detroit, MI
BroadcastMLB.tv

Key Storylines to Watch

  • Pitching Form: The Diamondbacks will start Brandon Pfaadt in this game. Pfaadt has gone 10-6 this season despite a high ERA of 4.76. He is giving up just over a hit per inning and will need to lock in to slow down the Tigers’ offense. Casey Mize gets the start for Detroit. He is 9-4 with a 3.40 ERA on the year.

  • Bullpen Usage: The Tigers’ bullpen operated well in the first game of this series. The Tigers only gave up one run to the Diamondbacks on Monday. Arizona has a bottom-five bullpen ERA this year and that should help the Tigers’ cause again tonight.

  • Team Momentum: The Tigers have been dominant at home. They have a 34-21 record there. The Diamondbacks have struggled on the road at 25-28. But the Tigers are just 3-7 over their last 10 games.


Best Player Props

PlayerPropValue
Eugenio SuárezHome RunsOver 0.5
Casey MizeStrikeoutsOver 5.5

  • Head-to-Head Results: The Tigers are 1-0 over the Diamondbacks for the season.

  • The first game of this series went under the total with just six total runs scored.

  • Arizona has scored just one run combined over its last three games.

Diamondbacks vs Tigers Model Projection

Projected Score: Tigers 5 – Diamondbacks 3
Win Probability: Tigers 65% | Diamondbacks 35%


Final Thoughts

The Tigers don’t have Tarik Skubal on the mound for this game. But they have a decent option in Casey Mize out there instead. Mize should get off to a strong start in this game and help the Tigers build an early lead. They will hold onto that lead thanks to a bullpen that is superior to that of Arizona. I’ll take the Tigers to win and cover the runline in this contest from Comerica Park.


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Home MLB Picks Arizona Diamondbacks vs Detroit Tigers Pick – 7/29/2025