The Tulane Green Wave will meet the UTSA Roadrunners in an American Athletic Conference matchup in college football on Thursday night. Tulane comes into this game with an unbeaten record in AAC play and they will try to move a step closer to another conference title game appearance with a win here. Before kickoff from the Alamodome, continue reading to get my Tulane vs UTSA prediction for this contest.
Our Tulane vs UTSA Pick
- Pick: Over 53.5
- Confidence: 4/5
Game Snapshot
- Matchup: Tulane Green Wave vs UTSA Roadrunners
- Date & Time: Thursday, October 30, 2025, 7:30 PM ET
- Venue: Alamodome, San Antonio, TX
- Broadcast: ESPN
Key Storylines
Tulane has a 6-1 record with a perfect conference record at 3-0. Their offense is balanced with quarterback Jake Retzlaff providing a threat as both passer and runner. That has created matchup problems for defenses that have to choose whether to prioritize stopping the run or the pass. The Green Wave defense has also had success, giving up 20 or fewer points to all three AAC opponents they have faced.
The headline for UTSA this season is their home form and their running game. Robert Henry Jr. is a genuinely explosive back who has rushed for 868 yards and nine touchdowns already this season. UTSA’s offense can go for big numbers at the Alamodome, but the Roadrunners gave up 55 points to North Texas on the road in their last game and they need to be better on defense here to get an upset win.
Quarterback Play
- Tulane: Jake Retzlaff has 1,428 passing yards, six passing touchdowns, and one interception through seven games. He also has 450 rushing yards with eight rushing touchdowns. He grades as an efficient dual-threat quarterback with the ability to make plays on the ground on designed runs and scrambles.
- UTSA: Owen McCown has 1,310 passing yards with 13 passing touchdowns and four interceptions this season. McCown has had solid moments and will need to be at his best to combine with Henry to outscore the Green Wave.
Betting Trends
- Tulane is 3-3-1 against the spread this season.
- UTSA is 3-4 against the spread going into this matchup.
- Tulane games have gone under the total five times in seven games.
- UTSA games have gone over their totals five times in seven games.
Tulane vs UTSA Model Projection
Score Projection: Tulane 30 – UTSA 27
Win Probability: Tulane 63%, UTSA 37%
Final Thoughts
I think that we are going to see a high-scoring game from the Alamodome on Thursday night. Both UTSA and Tulane are capable of moving the ball both on the ground and through the air. These two offenses will keep the defenses guessing throughout this matchup and we should see this game go over the total in what should be another entertaining game in the AAC.


 
  
  
 