Southern Miss and Louisiana Tech will meet in a non-conference matchup in college football on Saturday night. Both teams are off to 2-1 starts this year and will look for a significant win before diving back into conference play. Here, I give you the breakdown of both teams, including my Southern Miss vs Lousiana Tech prediction for this Saturday night matchup.
Our Southern Miss vs Louisiana Tech Pick
- Pick: Louisiana Tech -3.5
- Confidence: 3/5
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Game Snapshot
- Matchup: Southern Miss Golden Eagles vs Louisiana Tech Bulldogs
- Date & Time: Saturday, September 20, 2025, 7:30 p.m. EDT
- Venue: Joe Aillet Stadium, Ruston, LA
- Broadcast: ESPN+
Key Storylines
- Southern Miss Offense: The Golden Eagles have showcased a potent offense, averaging 31 points per game. Quarterback Braylon Braxton has been efficient, completing 73.3% of his passes for 279 yards and two touchdowns in their recent 38-22 victory over App State.
- Louisiana Tech Defense: The Bulldogs’ defense has been impressive, allowing only 12.3 points per game. Their recent 49-14 win over New Mexico State highlighted their defensive prowess, as did holding LSU to just 23 points in Death Valley a couple of weeks ago.
- Turnover Battle: Southern Miss has forced six turnovers this season, while Louisiana Tech has forced seven. Protecting the ball will be crucial for both teams in this tightly contested matchup.
Quarterback Play
- Southern Miss – Braylon Braxton: Braxton has been a steady presence under center, demonstrating accuracy and good decision-making. He has seven touchdown passes to just two interceptions and will try to avoid turnovers to give his team a chance to win on the road here.
- Louisiana Tech – Blake Baker: Baker has shown dual-threat capability, contributing both through the air and on the ground. He hasn’t thrown a pick yet this year and will try to keep that streak alive this weekend.
Betting Trends & H2H
- Louisiana Tech: The Bulldogs are 3-0 against the spread to start this season.
- Southern Miss: The Golden Eagles have been competitive, covering the spread in two of their three games this season.
- Head-to-Head: Southern Miss is 36-17 all-time against Louisiana Tech.
Southern Miss vs Louisiana Tech Model Projection
- Score Projection: Southern Miss 21 – Louisiana Tech 27
- Win Probability: Southern Miss 35%, Louisiana Tech 55%
Final Thoughts
This matchup between Southern Miss and Louisiana Tech is expected to be a closely contested game. But I think that Louisiana Tech has the upper hand at home in this contest. The Bulldogs should take advantage of the fact that this is Southern Miss’ first road game of the year and they could struggle compared to what we’ve seen from the Golden Eagles through three games. I’ll lay the points with Louisiana Tech on Saturday night.
