The Liberty Flames will face the Jacksonville State Gamecocks on Saturday in Jacksonville. This is the first Conference USA matchup of the season for both of these teams and it is a game that could end up deciding who plays in the CUSA championship game later in the year. Before this huge Group of Five game kicks off on Saturday, keep reading to get my Liberty vs Jacksonville State prediction.
Our Liberty vs Jacksonville State Pick
- Pick: Jacksonville State +7.5
- Confidence: ★★★☆☆
- Get Your Bonus Bets: Click the Claim Bonus button to bet $5 and get $300 in bonus bets INSTANTLY and over $200 off NFL Sunday Ticket with our DraftKings Sportsbook bonus!
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+ 
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Bet $5, Get $300 in Bonus Bets Instantly + Over $200 Off NFL Sunday Ticket
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Promo Code: Click To Claim
Gambling Problem? Call or TEXT 1-800-Gambler 21+
Game Snapshot
- Matchup: Liberty Flames vs Jacksonville State Gamecocks
- Date & Time: Saturday, September 6, 2025, 12:00 PM ET
- Venue: AmFirst Stadium, Jacksonville, AL
- Broadcast: CBS Sports Network
Liberty vs Jacksonville State Odds
| Betting Line | Spread | Moneyline | Total |
|---|---|---|---|
| Liberty | -7.5 | -280 | 49.5 |
| Jacksonville State | +7.5 | +230 | 49.5 |
Key Storylines
Quarterback Play
- Ethan Vasko (Liberty): Vasko completed 15 of 22 passes for 197 yards and 3 touchdowns in the Flames’ season opener against FCS opponent Maine. This game will be a much bigger test for Vasko against their first FBS opponent of the year.
- Gavin Wimsatt (Jacksonville State): Gavin Wimsatt of the Gamecocks threw for 139 yards with no touchdowns and one interception in the season opener. He struggled against UCF and will try to rebound against a conference opponent after struggling against a Big 12 opponent.
Running Back Performances
- Liberty’s Running Game: Liberty rushed for 194 yards as a team in their season opener. But their rushing leader was their quarterback. Vasko rushed for 63 yards against Maine and the Flames will need more from their running backs to win this contest.
- Jacksonville State’s Running Game: Jacksonville State had 165 rushing yards in Week 1 and that number exceeded their total of passing yardage. Cam Cook led the Gamecocks with 75 yards on the ground on 4.4 yards per carry and he will look to lead another productive day on the ground.
Betting Trends & H2H
- Liberty failed to cover the spread in their first game of the season against Maine.
- Jacksonville State covered the spread as an underdog despite losing to UCF in Week 1.
- Jacksonville State and Liberty have played three times all-time. The Gamecocks have won three of those four matchups and won the most recent meeting in 2024.
Liberty vs Jacksonville State Model Projection
- Score Projection: Liberty 28 – Jacksonville State 24
- Win Probability: Liberty 65%, Jacksonville State 35%
Final Thoughts
I think that Jacksonville State will cover the spread as a home underdog in this conference game. I was not fully convinced by Liberty’s performance against Maine in their opener and I think that the Gamecocks will be better than they were last week against a Big 12 opponent. Liberty should ultimately win this game on the road, but I could easily see Jacksonville State winning outright and I’ll take the points with the home dog.
