In Week 2 of the NFL season, our best bet features a matchup between the Buffalo Bills and New York Jets. Both teams played close games in the opening week of the season and will look for wins in less stressful situations here. Below, you will find my NFL best bets this week and some insights into why I’m going that way in the betting markets.
NFL Best Bets For Week 2
NFL Best Bet #1: Jets +6.5 (-110) over Bills
My best bet for NFL Week 2 is for the New York Jets to cover the spread as a home underdog against the Buffalo Bills. The Jets covered the spread as a home dog against the Pittsburgh Steelers last week. And while the Jets’ defense could struggle at home for the second week in a row against a potent Buffalo offense, the Jets should do enough offensively to keep this game within a touchdown.
2025 NFL Best Bets Record: 1-0-0 (+1.00 unit)
2024 NFL Best Bets Record: 16-19-1 (-4.85 units)
2023 NFL Best Bets Record: 23-15-1 (+6.91 units)
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Stay ahead of the action this season with our expert-curated NFL best bets for every week of the 2024/25 schedule. At ATS.io, our team of seasoned analysts combines years of experience with in-depth statistical analysis to bring you the most reliable NFL picks and predictions. Whether you’re looking for the sharpest insights on spreads, moneylines, totals, or prop bets, our experts dive deep into the data to uncover the best opportunities across every market.
From understanding team trends to evaluating player matchups, our weekly NFL best bets are designed to give you an edge. Trust our expertise and commitment to accurate, data-driven picks, all tailored to help you make informed decisions and enjoy the excitement of the NFL season. Check back each week to stay updated with our top bets and insights.
Overview Of NFL Best Bets At ATS.io
With a ton of NFL betting options available each week, it is hard to decide what to bet on and what to avoid. Fortunately, our expert NFL handicappers do the hard work for you, breaking down each game and coming up with the best ways to find value in the National Football League. Be sure to come back here each week for the latest best bets in the NFL, from the biggest games of the week to the least attractive games on the board.
What is the best type of bet on the NFL?
When it comes to NFL betting, Moneyline wagers are often touted as a top choice. They are considered one of the easiest NFL football bets to win. The reason behind this preference is that pro football games frequently adhere to expected outcomes. Betting on the Moneyline can be a reliable strategy for NFL bettors. To enhance your success rate, consider utilizing our NFL expert picks to inform your betting decisions.
How Do We Make Our Best NFL Bets?
Our NFL best bets are selected using a number of methods. Our NFL betting experts use their own modeling to set their own lines, comparing them to the actual NFL odds from online sportsbooks to determine where there is value in the betting market. But that is just the beginning of the processes that they use to determine which wagers make the cut for each week of the NFL schedule.
Along with doing their own modeling, our NFL handicappers make sure to examine the statistics, injury reports, and all other pertinent information surrounding each team going into each week. While the NFL is the hardest betting market to beat year in and year out, our team does everything it can to find the most value in the marketplace every week.
Types of bets ATS.io Makes on the NFL
At ATS.io, we cover NFL betting markets like props, parlays, and teasers on the pages that we have linked to below. For our top picks each week, bettors will generally find one of the following types of bets here on a regular basis.
Bets With The Point Spread
The point spread is by far the most popular betting market when wagering on football. The goal of this market is for bettors to predict which side will end up with a higher score after the point spread is applied to each game. For example, if a team is favored by six points in a game, they have to win by seven or more points to cover the spread. If a team is a six-point underdog, they just need to lose by five or fewer points or win the game in order to cover.
In the NFL, no point spread is safe until a game is fully over. Late offensive and defensive touchdowns can have an impact on any point spread wager in any game, and bettors should be mindful of that before they place any wagers in this market every year in the NFL.
Over/Under Bets
Another incredibly popular type of wager is the over/under, which asks bettors to predict how much scoring will happen in each NFL game. Sportsbooks will set a total for each game, and bettors are then asked to predict whether the score of the game will go over or under that amount. For example, a sportsbook may set a total for a game at 45.5 points. If the total score of the game is 46 points or more, the over will be the winner, while 45 or fewer points will mean the under is the winning side.
The key to betting on over/unders in the NFL is understanding the ways both teams play football. Everything from individual matchups to the tempos that teams use can greatly impact the outcome of any over/under bet. Fortunately, we break down all of those elements before recommending any over/under wager.
Moneyline Bets
Moneyline betting is incredibly easy for bettors to understand, as the goal is to simply predict which team will win each NFL game. Of course, predicting which team will win any NFL game is easier said than done, as even the worst teams in the NFL find a way to spring upsets on their opponents from time to time. But we work to find instances where the chance of winning is greater than the odds for that game, to deliver maximum value in the moneyline betting market.
Do we use AI or a computer to generate our best bets?
Yes using the latest AI technology and computer algorithms are a part of the betting strategy here at ATS, as our handicappers do their own modeling using data that they collect from each NFL season. All of that work is done by our in-house handicappers to identify unique betting opportunities that cannot be found anywhere else. That is what makes ATS your one-stop shop for all of the best NFL bets this week and every week.
Want More? Check Out Our Other NFL Picks & Predictions
Along with our best NFL bets this week listed above, bettors should click the links below to get our best picks in a number of other areas of NFL betting.
