Los Angeles Rams vs Arizona Cardinals Prediction - 12/7/2025
Updated December 5, 2025
Updated December 5, 2025
The Los Angeles Rams head into Week 14 as heavy favorites against the Arizona Cardinals in a game that looks like a one‑sided affair on paper. The Rams are riding high with a 9‑3 record and are tied at the top of the NFC West going into Sunday's play. The Cardinals are 3‑9 and have struggled mightily all season, making this a key opportunity for Los Angeles to help their chances of winning the division. Here, I break down this matchup in the NFC West and make my Rams vs Cardinals prediction in Week 14.
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For the Rams, Matthew Stafford leads one of the NFL’s most efficient offenses. He enters the game with 3,073 passing yards, 32 touchdowns, and just 4 interceptions. His connection with his receiving targets like Puka Nacua and Davante Adams has been impressive all year long. On the other side, Jacoby Brissett has kept the Cardinals afloat as well as possible, but his offense lacks the explosive weapons and pass protection to consistently challenge elite defenses.
Score Projection: Rams 27 – Cardinals 21
Win Probability: Rams 78%, Cardinals 22%
The Rams should be able to come away with an important in this game to get to 10 wins on the year and stay on top of the NFC West. But I'm taking the points with Arizona here, as Brissett should be able to lead just enough scoring drives to keep this game within a possession at home.
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