New York Knicks vs Minnesota Timberwolves Prediction & Prop Bets – 12/23/2025

The New York Knicks and Minnesota Timberwolves will face off on Tuesday in the final game for both teams before Christmas Day. Both clubs have found success this season but the Wolves are sizable favorites at home with the Knicks resting several key players. Before tip-off from Minneapolis, you will find my Knicks vs Timberwolves prediction below, as we try to make sense of the injury report leading up to this game.

Our Knicks vs Timberwolves Pick

Game Snapshot

• Matchup: New York Knicks @ Minnesota Timberwolves
• Date & Time: Tuesday, December 23, 2025, 8:00 PM ET
• Venue: Target Center, Minneapolis, Minnesota
• Broadcast: NBA League Pass

Key Storylines

The Knicks enter this contest off a sensational 47-point outburst from Jalen Brunson in a 132‑125 victory over the Miami Heat, getting their eighth win in nine games. However, New York’s injury report is concerning going into this matchup. Brunson has been announced to sit due to load management and ankle soreness, and OG Anunoby is also out with left ankle issues. Additional role players such as Guerschon Yabusele, Miles McBride, and Landry Shamet are sidelined. That will leave the Knicks’ rotation short‑handed and less potent on both offense and defense.

Minnesota comes in with positive momentum, having rallied for a 103‑100 win against the Milwaukee Bucks. Anthony Edwards led the Wolves with 24 points and Donte DiVincenzo supplied key perimeter shooting in the comeback. Rudy Gobert has been a force on the boards, and Julius Randle continues to provide scoring and physicality. That said, Minnesota has its own injury concerns. Jaden McDaniels exited the recent Bucks game early with a hip injury and is questionable, potentially thinning the Wolves’ wing depth. But the Wolves look much healthier than the Knicks going into this game and they will try to use that to their advantage today.

Head-to-Head & Betting Trends

• The Knicks and Timberwolves have met this season with New York winning their previous meeting 137‑114. But the Knicks look a lot different going into this game than they did in that contest.
• The Knicks are 18-11 against the spread going into this contest.
• Minnesota is 11-18 against the spread for the season.
• The Knicks have gone over the total in 16 of their first 29 games.
• The under has hit in 16 of the Timberwolves’ 29 games.

Best Player Props to Watch

Knicks vs Timberwolves Model Projection

Final Thoughts

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.