Cleveland Cavaliers vs Houston Rockets Prediction – 12/27/2025

The Cleveland Cavaliers and Houston Rockets will square off on Saturday night in Houston. Both teams enter this contest with winning records and looking to get a statement win over another likely playoff team. Here, I break down this matchup in the NBA and give you my Cavaliers vs Rockets prediction on Saturday night.

Our Cavaliers vs Rockets Pick

Game Snapshot

• Matchup: Cleveland Cavaliers @ Houston Rockets
• Date & Time: Saturday, December 27, 2025, 8:00 PM ET
• Venue: Toyota Center, Houston, Texas
• Broadcast: NBA League Pass

Key Storylines

• The Rockets are leaning on their stars for a home win, with Kevin Durant averaging 25.2 points per game and Alperen Sengun contributing 22.7 points and 9.4 rebounds. Sengun’s availability is listed as questionable due to calf tightness, a factor that could affect Houston’s frontcourt if he is limited.
• Houston’s offense is operating efficiently, ranking among the league’s top scoring units and also leading in rebounds per contest. The Rockets’ field goal percentage is strong, and their home record is impressive this season at 8-2.
• Cleveland’s injury report includes Max Strus out with a foot issue and Larry Nance Jr. out due to a calf concern, while the core of Donovan Mitchell and Evan Mobley remains active. Mitchell is a high-usage offensive force, averaging over 30 points per game, and Mobley adds double-digit scoring alongside strong rebounding and defense from the forward spot.
• The Cavaliers have struggled on the road this season, going 6-7 away from Rocket Arena. They are coming off a Christmas Day loss to the New York Knicks, where Cleveland blew a double-digit lead against New York.
• Houston is coming off a win on Christmas against the Los Angeles Lakers. The Rockets held the Lakers under 100 points in that game and blew the Lakers out in a convincing performance on the road.

Head-to-Head & Betting Trends

• Houston beat Cleveland by 10 points in Cleveland in their first meeting of the regular season.
• Houston is 16-12 against the spread so far this season.
• Cleveland is 10-22 against the spread going into this game.
• The Rockets are 17-10-1 to the over going into this matchup.
• Cleveland is 16-16 in the over/under market going into this contest.

Best Player Props to Watch

Cavaliers vs Rockets Model Projection

Final Thoughts

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.