Tulane Green Wave vs Ole Miss Rebels Prediction - CFP First Round

Updated December 7, 2025


Updated December 7, 2025

The Tulane Green Wave and Ole Miss Rebels have been paired up in the first round of the 2025 College Football Playoff. Ole Miss has a long winning streak over the Green Wave that dates back many recruiting cycles. They are favored to win this game and extend that streak while advancing to the next round of playoff competition. Before kickoff from Oxford, continue reading to get my Tulane vs Ole Miss prediction from Mississippi.
Spread | Moneyline | Total |
|---|---|---|
Ole Miss –16.5 | Ole Miss –950 / Tulane +625 | 55.5 points |
For Tulane, the offense runs through Jake Retzlaff. He scored two short touchdown runs in the AAC title game and helped Tulane seize momentum with a balanced offensive attack. Trinidad Chambliss is the starting quarterback for Ole Miss. He has been electrifying for the Rebels this season, throwing for just over 3,000 yards and throwing only three interceptions. If he can take care of the football and let Ole Miss' advantages in the trenches shine, Ole Miss could roll over the Green Wave again.
Score Projection: Ole Miss 38 – Tulane 27
Win Probability: Ole Miss 78%, Tulane 22%
Ole Miss should be able to win at home to move onto the quarterfinals of the College Football Playoff. But I don't think this is going to be a complete blowout either. I'm going to take the points with Tulane, who are just unpredictable enough offensively with Retzlaff at quarterback to keep things respectable and represent the AAC well in the playoff.
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