Portland Trail Blazers vs New Orleans Pelicans Prediction – 12/11/2025

The Portland Trail Blazers will travel to the Crescent City to face the New Orleans Pelicans on Thursday night in a Western Conference contest. Both teams are well below the .500 mark this season and they will try to take advantage of this opportunity to beat another struggling opponent. Here, I break down this contest from New Orleans and make my Trail Blazers vs Pelicans prediction for Thursday’s game.

Our Trail Blazers vs Pelicans Pick

Game Snapshot

• Matchup: Portland Trail Blazers @ New Orleans Pelicans
• Date & Time: Thursday, December 11, 2025, 7:00 PM ET
• Venue: Smoothie King Center, New Orleans, Louisiana
• Broadcast: NBA League Pass

Key Storylines

• The Pelicans are struggling mightily going into this game. They are 3-22 and have lost seven games in a row. New Orleans has the worst record in the Western Conference and the worst record in the NBA as a whole.
• Portland has lost two straight games and four of their last five outings overall. The Trail Blazers are allowing over 120 points per game on defense, as they have joined the Pelicans as one of the worst defensive teams in the NBA for the season.
• Both teams are dealing with some injury issues going into this contest. The Pelicans are without Zion Williamson and Dejounte Murray, while Jordan Poole is questionable to take part in this matchup. The Trail Blazers are set to be without Jrue Holiday, Donovan Clingan, and Matisse Thybulle. Robert Williams III is also questionable to take part in this matchup.

Head-to-Head & Betting Trends

• Portland won the first game between these teams this season by a score of 125-117 in New Orleans.
• The Pelicans are 14-10-1 against the spread so far this season.
• The Trail Blazers are 13-11 against the spread through their first 24 games this year.
• The over has hit in 15 of Portland’s first 24 outings this season.
• The over is 15-10 in games featuring the Pelicans during the 2025-26 campaign.

Best Player Props to Watch

Trail Blazers vs Pelicans Model Projection

Final Thoughts

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.