Chicago Cubs vs Milwaukee Brewers Game 5 Prediction - 10/11/2025
Updated October 10, 2025
Updated October 10, 2025
The series between the Chicago Cubs and Milwaukee Brewers will come down to Game 5 on Saturday at American Family Field in Milwaukee. The Cubs forced this finale with a 6–0 shutout win in Game 4. The home team has won all four games of this series so far and the Brewers will try to continue that trend to advance to the NLCS. Before the first pitch in Saturday's Game 5, you can find my Cubs vs Brewers Game 5 prediction below.
No starters have been officially announced yet for this game. But no matter who starts this game on the mound, we should see both bullpens get heavily involved. Both starters will likely be on short leashes. Names like Shota Imanaga of the Cubs and Jacob Misiorowski of the Brewers have been floated as pitchers who could feature prominently in this game. But some bettors may want to wait for confirmation before locking any bets in for this contest.
Player | Prop |
|---|---|
Ian Happ | Over 1.5 Total Bases |
Michael Busch | Under 1.5 Total Bases |
Jackson Chourio | Over 0.5 Home Runs |
Score Projection: Cubs 4 – Brewers 5
Win Probability: Cubs 42%, Brewers 58%
The home team has had the upper hand throughout this series so far and I expect that to be the case again in this winner-take-all matchup. The Brewers will have a ton of crowd noise in their corner here. More importantly, they have the best record in the league this season and they should get the job done at home to set up an NLCS matchup with the Los Angeles Dodgers.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
Affiliate Disclosure
ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
