College Football Week 10: 5 Games That Could Swing CFP Futures

Updated November 6, 2026


Updated November 6, 2026

Week 10 might be the best college football slate of the year, especially when it comes to ranked-on-ranked matchups and College Football Playoff implications. If there was ever a Saturday to park yourself on the couch and watch football for 12 straight hours, this is probably it.
There are so many good games that Oregon vs. Ohio State didn't even make my list (sorry, Duck and Buckeye fans). That's a matchup we probably would've expected to be a top-five or top-10 showdown heading into the season, and it still has plenty of playoff implications of its own.
Below, I'll break down the five biggest Week 10 matchups, what makes each one interesting, and how the results could shake up the CFP futures market. I'll also look at the current Polymarket odds to see what traders are expecting heading into Saturday.
Don't let the No. 11 next to Notre Dame's name fool you. These are two of the best teams in college football, and the advanced numbers back that up. The Fighting Irish rank third nationally in SP+, just ahead of fifth-ranked Miami. Both offenses also rank in the top three in EPA per play, so this has all the makings of a great matchup.
Unfortunately, Miami will be without star receiver Malachi Toney, who suffered an ankle injury in practice this week. Toney has already put up 1,027 receiving yards and 13 touchdowns this season, so that's a pretty big loss for the Hurricanes.
Notre Dame is now a heavy favorite, trading at 71 cents to win on Polymarket, with the Irish -6.5 priced at 57 cents. Our Miami vs. Notre Dame model prediction still sees value on the Irish, even at the current prices.
There's also some unfinished business from last season. Miami beat Notre Dame 27-24 in the 2025 opener, a result that eventually helped the Hurricanes get into the playoff while the Irish were left out. Now Notre Dame gets a chance to return the favor at home, and the stakes are even higher this time around.
Notre Dame currently has a 76% implied chance to make the CFP on Polymarket, along with the second-best national championship odds at 15%. But a loss here could change everything. The committee already made it clear that it isn't overly impressed with the Irish's résumé by ranking them 11th, and they don't have another currently ranked opponent left on the schedule after Miami.
If Notre Dame loses at home to a shorthanded Hurricanes team, I wouldn't be surprised to see its playoff chances fall below 50%. On the other hand, a win over the No. 1 team in the country would give the Irish the signature victory they've been missing.
Here we go again. Georgia and Ole Miss met twice last season, including in the College Football Playoff semifinals, and now they're facing off for a third time in just over a year. And for the Rebels, this one could have some serious playoff implications.
Ole Miss enters as a home underdog, trading at 39 cents to win on Polymarket, while the Rebels +3.5 is priced at 50 cents.
Our Georgia vs. Ole Miss model projection sees value on the Bulldogs' team total over 30.5 points, and it's not hard to see why. Georgia is averaging 41 points and 450.9 yards per game, while Ole Miss ranks 97th nationally in total defense, allowing 383.9 yards per game.
Ole Miss might have more riding on this game than just about anyone else in Week 10. The Rebels currently have a 59% implied chance to make the CFP on Polymarket, but a loss would drop them to 6-3. And with no currently ranked opponents left on their schedule, they wouldn't have many chances to impress the committee down the stretch.
Could a 9-3 Ole Miss team still make the playoff? It's possible, but I wouldn't count on it. No team with three regular-season losses has made the 12-team CFP yet, and there are already two-loss teams like Alabama and Texas ranked ahead of the Rebels. That makes Saturday's game about as close to a must-win as it gets for Ole Miss.
Saturday's slate also includes another chapter of the Holy War, although I'm not sure who decided a rivalry game this big should kick off at 10 a.m. local time in Salt Lake City (noon ET).
There's an interesting role reversal from last season, too. Last year, BYU entered this matchup undefeated and playing at home. This time, it's Utah that's unbeaten and sitting higher in the CFP rankings under first-year head coach Morgan Scalley.
Utah is favored at 63 cents to win on Polymarket, giving the Utes a 63% implied chance of beating their rivals.
Utah -4.5 is also priced at 50 cents, and our BYU vs. Utah model prediction sees some value on the Utes. The numbers help explain why, too. Utah's defense is holding opponents to a 35.5% success rate, while the Utes rank seventh nationally in offensive success rate.
But BYU might need this win even more. The Cougars currently have just a 36% implied chance to make the CFP on Polymarket, and another loss would put them in a tough spot.
Even with their impressive win over Notre Dame a few weeks ago, a two-loss BYU team could find itself on the outside looking in, especially if it misses the Big 12 Championship Game. A road win over No. 3 Utah, though, would be a huge boost to its playoff chances.
Next up, we've got two teams that many fans would probably consider the most overrated in the first CFP rankings.
Alabama came in at No. 5 despite losing two of its last three games, including an embarrassing road loss to Tennessee (more on the Volunteers in a minute). Meanwhile, LSU sits at No. 14 with a 6-2 record, even though its best win is over a 5-3 Clemson team.
But LSU's underlying numbers tell a different story. The Tigers rank fourth nationally in SP+ and first in opponent-adjusted net EPA per play, suggesting they're better than their résumé might indicate. That helps explain why LSU is favored at home, trading at 68 cents to win on Polymarket, with LSU -6.5 priced at 50 cents.
Our Alabama vs. LSU model prediction also sees some value on over 52.5 points. There's plenty of offensive firepower on both sides, with LSU averaging 40.1 points per game and Alabama not far behind at 38.2.
What's interesting is how differently a loss could affect these two teams. LSU would fall to 6-3 with games against Texas and at Tennessee still remaining, making its path to the playoff much more difficult.
Alabama, on the other hand, seems to have more room for error, at least according to the committee. Even with a loss, the Crimson Tide would have three winnable games left against Vanderbilt, Chattanooga, and Auburn.
That helps explain why Alabama still has a 71% implied chance to make the CFP on Polymarket, despite being a pretty sizable underdog this weekend.
Last but not least, we've got a border rivalry between Kentucky and Tennessee. The Wildcats have been one of the biggest surprises in college football this season under first-year head coach Will Stein, climbing all the way to No. 6 in the first CFP rankings. But are they really the sixth-best team in the country? I'm not so sure.
Kentucky has been one of the luckiest teams in college football this year. The Wildcats needed successful two-point conversions in overtime to beat both South Carolina and LSU by identical 35-34 scores. They've also benefited from a +13 turnover margin, and despite their 7-1 record, they rank just 31st nationally in SP+.
That helps explain why Kentucky is trading at just 33 cents to win on Polymarket, despite being ranked seven spots ahead of Tennessee. The Wildcats are 6.5-point underdogs on the road, with Kentucky +6.5 priced at 50 cents.
Our Kentucky vs. Tennessee model projection also sees some value on over 49.5 points. Both teams are averaging more than 32 points per game, and Kentucky's defense ranks just 70th nationally in scoring defense, allowing 24.8 points per game.
And if you think Kentucky's odds to win this game seem low, take a look at its playoff chances. The Wildcats currently have just a 35% implied chance to make the CFP on Polymarket, which is surprisingly low for a one-loss SEC team ranked No. 6 in the country.
But then you look at what's left on their schedule: Tennessee, Florida, Missouri, and in-state rival Louisville. That's three straight ranked SEC opponents before the regular-season finale. Kentucky will likely need to win at least three of those four games to feel good about its playoff chances, and a blowout loss in Knoxville could send the Wildcats tumbling down the CFP rankings.