Video: Patriots vs Bills Prediction & Preview From Highmark Stadium - 10/4/2026
The Buffalo Bills will host the New England Patriots in NFL Week 4 action on October 4, 2026. We have boots on the ground in Buffalo, and you can find our short breakdown of this contest on location from Highmark Stadium. In this video, you will find:
- A discussion about the Bills winning despite turnover issues
- Quarterback issues in New England
- Our best bet for this contest between AFC East rivals
Buffalo is favored by a touchdown at home against the Patriots in a game that will have major implications for the division race between these teams. Buffalo is trying to create major separation at the top of the AFC East, while the Patriots are looking to avoid falling three games behind the Bills in the standings in just one month.
Click here to get our full Patriots vs Bills prediction.
Click here to get all of our NFL best bets this week.
