Indianapolis Colts vs Tennessee Titans Prediction, Odds & Picks – 10/13/2024

In Week 6 of the NFL season, the Indianapolis Colts will visit the Tennessee Titans in an AFC South rivalry matchup. Indianapolis is a one-point favorite going into this contest, while the total for the game is set at 42.5 points. With quarterback play on both sides being a hot-button issue, this should be an interesting game from Nashville, and you can get our NFL betting picks for Colts vs Titans right here.

Colts Navigating Anthony Richardson Injury Situation

The Indianapolis Colts lost a heartbreaker last week, falling against the Jacksonville Jaguars by a score of 37-34. Joe Flacco was the starting quarterback in that game for Indianapolis, replacing the injured Anthony Ricardson. This week, there will be questions about which quarterback will take the field and which quarterback should take the field for the Colts in Tennessee.

Along with quarterback questions, the Colts are also dealing with questions on their defense. Indianapolis was torched by the Jaguars last week and has struggled to get stops against several opponents early in the year. Against a Titans team dealing with quarterback issues of their own, Indianapolis has to be better on defense to avoid getting embarrassed on the road.

Can Titans Build On Pre-Bye Momentum?

Before their Week 5 bye week, the Tennessee Titans got a win on Monday Night Football against the Tennessee Titans. They did that despite quarterback Will Levis suffering an injury and backup quarterback Mason Rudolph only managing 85 passing yards in his place. This week, Levis is listed as questionable as the Titans look for a second straight win.

Whether or not Levis can play this week should not be the question. Instead the question should be whether or not Levis should play. He has four touchdowns and six interceptions early in his 2024 campaign, which are not acceptable marks for a professional quarterback through the first few weeks of the year. His turnovers have continued to kill his team’s chances of winning games, something that needs to stop this week if he suits up.

Colts vs Titans Matchup History

The Indianapolis Colts and Tennessee Titans have met 59 times heading into their game this Sunday. Indianapolis has got the better of this division rivalry over the years, winning 37 of those 59 games, including each of their two meetings during the 2023 season. The Colts will look to extend their winning streak over the Titans with a win in this contest.

Colts vs Titans Prediction

Our best bet for Colts vs Titans in Week 6 is for the Indianapolis Colts to bounce back from their loss to the Jaguars to win on the road. The Colts are more dynamic offensively no matter who their quarterback is this week. And with the Titans struggling to move the ball through the air, the Colts defense should be able to key in on the running game of Tennessee.